Effect of Corneal Preservation time on Long-Term Graft Success- Reading Center

CIARC（前身为SMRC）在CWRU和大学医院眼科研究所，成立于1999年， 20年前，作为一个阅读中心，研究公司研究药物的影响， 手术和角膜内皮保存介质（43-51）已成为 自2000年以来，SMAS的内皮图像分析阅读中心。CIARC已经成为一个 由于开发了内皮成像分类系统，成为该领域的领导者 采用双重分级和判定的质量和可变帧ECD确定 系统（2，5-7）在这段时间内，CIARC分析了超过229个眼库图像 以及仅来自SMAS的>3000个临床图像集。在过去的三年里，CIARC 将其努力扩展到镜面和共聚焦图像的内皮图像分析 遵循EK（32，42）以及形态测量图像分析技术在 与本提案相关的SMAS图像。

The CIARC (formerly SMRC) at CWRU and University Hospitals Eye Institute, established over 20 years ago as a reading center for corporate studies examining the effect of medications, surgery, and preservation media on the corneal endothelium (43-51), has served as the endothelial image analysis reading center for the SMAS since 2000. The CIARC has become a leader in the field as a result of its development of a classification system for endothelial image quality and variable frame ECD determination employing a dual grading and adjudication system.(2, 5-7) Over this period of time the CIARC has analyzed over 229 eye bank images and >3000 clinical image sets from the SMAS alone. In the past three years the CIARC has extended its efforts to endothelial image analysis of both specular and confocal images following EK (32, 42) and the application of morphometric image analysis techniques to the SMAS images which have relevance to this proposal.