Human Sample Acquisition Core (HSAC)

人体样本采集核心 (HSAC)

• 批准号: 8713961
• 负责人: KENNETH J. PIENTA
• 金额: $ 11.15万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8713961
• 关键词: Address; Aspirate substance; Autopsy; Biopsy; Blood; Bone Marrow; Cells; Clinic; Clinical; Collection; Consent; Ensure; Human; Individual; Informatics; Leukocytes; Malignant neoplasm of prostate; Mesenchymal; Metastatic Neoplasm to the Bone; Michigan; Neoplasm Circulating Cells; Pathologist; Pathology; Patient Participation; Process; Prostate; Research Infrastructure; Resources; Sampling; Serum; Tissue Banking; Tissue Banks; Tissues; Translational Research; Universities; human biological material; neoplastic cell; operation; programs; quality assurance

The aim of the TMEN Human Sample Acquisition Core (HSAC) is the collection of human biological material with associated clinical information to facilitate translational research of the individual projects. This core will build on the already existing resources of the University of Michigan Prostate SPORE to make the best use of available resources. Quality assurance is maintained through the staff of the Prostate SPORE pathologists. Clinical consent and patient participation is conducted by Dr. Pienta through the Prostate Cancer Clinic at the University of Michigan. The informatics infrastructure of the Human Sample Acquisition Core is provided by an instance of caTissue as hosted by the Prostate SPORE and is coordinated by the Directors of the Division of Pathology Informatics. Specifically, the aim of the HSAC is to (i) collect blood for circulating tumor cells, white blood cells, and serum, (Ii) to collect bone marrow from aspirates and biopsies for mesenchymal cells, disseminated tumor cells and serum, and (iii) collect metastatic tissue from the University of Michigan Rapid Autopsy Program (RAP). Support for tissue banking and collection of tissue from the RAP is provided by the SPORE. Support is only being requested to collect and process blood and bone marrow.

TMEN人类样本采集核心（HSAC）的目的是收集人类生物样本。 具有相关临床信息的材料，以促进各个项目的转化研究。 这个核心将建立在密歇根大学前列腺孢子的现有资源， 充分利用现有资源。质量保证是通过工作人员的 前列腺孢子病理学家。临床同意和患者参与由Pienta博士进行 通过密歇根大学前列腺癌诊所。的信息学基础设施， 人体样本采集核心由前列腺组织托管的caTissue实例提供。 由病理学信息学部主任协调。 具体地，HSAC的目的是（i）收集用于循环肿瘤细胞、白色血细胞的血液，以及 血清，（Ii）从抽吸物和活检组织中收集骨髓，以获得间充质细胞，播散性 肿瘤细胞和血清，和（iii）从密歇根大学快速尸检收集转移组织 方案（RAP）。组织库和RAP组织收集的支持由 孢子。目前只要求在收集和处理血液和骨髓方面提供支助。