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Diagnosis of Crystal-Based Arthropathies via Raman Spectroscopy

Diagnosis of Crystal-Based Arthropathies via Raman Spectroscopy
通过拉曼光谱诊断晶体关节病
批准号：
8528336
负责人：
Ozan Akkus
金额：
$28.86万
依托单位：
CASE WESTERN RESERVE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-09-01 至 2015-08-31
来源：
https://reporter.nih.gov/project-details/8528336
关键词：
AdoptionAffectAliquotArthritisAspirate substanceBiomedical EngineeringCalcium OxalateCalcium PyrophosphateCalcium Pyrophosphate DihydrateChemicalsClinicClinicalCollaborationsCollectionCommunitiesComplexCost SavingsCystineDataDecision MakingDepositionDeteriorationDevicesDiagnosisDiagnostic ProcedureDiseaseEngineeringEvaluationFacilities and Administrative CostsFeverFiltrationFoundationsGoalsGoldGoutHeadHealth systemHome environmentHospitalsImageImpairmentInflammatoryInvestigationJointsKidneyLasersLeadLettersLightLocationMapsMedicalMethodsMicroscopeMicroscopicModalityMorbidity - disease ratePainPathologyPatientsPerceptionPharmaceutical PreparationsPhotonsPhysiciansPreparationPrevalencePrimary Health CareProcessPseudogoutQuality ControlQuality of lifeRaman Spectrum AnalysisReactionResearchResortResourcesRheumatologyRoentgen RaysSamplingSensitivity and SpecificitySerumSignal TransductionSpottingsSwellingSymptomsSyringesTechniquesTechnologyTimeTrainingTranslatingUrateValidationWorkXanthinesarthropathiesbasecalcium phosphateclinical Diagnosisclinical practiceclinically relevantcostcost effectiveimprovedinstrumentmedical specialtiesmillimeternovelpatient populationpoint of carepolarized lightprimary care settingprogramsprototyperheumatologistscreeningtooluser-friendly

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中文摘要
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英文摘要
DESCRIPTION (provided by applicant): The overall goal of the proposed study is to assess the efficiency of diagnosing crystals leading to inflammation of joints using a cost-efficient device which uses laser light. The study will fabricate the device, collect samples from the clinic and determine the sensitivity of the method in comparison to existing clinical diagnostic methods.
期刊论文(5)
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科研奖励(0)
会议论文
Wide-field Raman imaging of dental lesions.
牙齿病变的宽视场拉曼成像。
DOI： 10.1039/c4an00164h
发表时间： 2014
期刊： The Analyst
影响因子： --
作者： [Yang,Shan, Li,Bolan, Akkus,Anna, Akkus,Ozan, Lang,Lisa]
通讯作者： Lang,Lisa
Raman spectral classification of mineral- and collagen-bound water's associations to elastic and post-yield mechanical properties of cortical bone.
矿物质和胶原蛋白结合水与皮质骨弹性和屈服后机械性能关联的拉曼光谱分类。
DOI： 10.1016/j.bone.2015.07.024
发表时间： 2015
期刊： Bone
影响因子： 4.1
作者： [Unal,Mustafa, Akkus,Ozan]
通讯作者： Akkus,Ozan
Laser Wavelength Dependence of Background Fluorescence in Raman Spectroscopic Analysis of Synovial Fluid from Symptomatic Joints.
有症状关节滑液拉曼光谱分析中背景荧光的激光波长依赖性。
DOI： 10.1002/jrs.4338
发表时间： 2013
期刊： Journal of Raman spectroscopy : JRS
影响因子： --
作者： [Yang,Shan, Li,Bolan, Slipchenko,MikhailN, Akkus,Anna, Singer,NoraG, Yeni,YenerN, Akkus,Ozan]
通讯作者： Akkus,Ozan
A customized Raman system for point-of-care detection of arthropathic crystals in the synovial fluid.
定制的拉曼系统，用于即时检测滑液中的关节病变晶体。
DOI： 10.1039/c3an02062b
发表时间： 2014
期刊： The Analyst
影响因子： --
作者： [Li,Bolan, Yang,Shan, Akkus,Ozan]
通讯作者： Akkus,Ozan
Cartilage Repair by Condensed Mesenchymal Stem Cell Delivery via Collagen Fabric
  • 批准号：
    9441710
  • 项目类别：
  • 资助金额：
    $20.92万
  • 财政年份：
    2017
  • 负责人：
    Ozan Akkus
  • 依托单位：
    CASE WESTERN RESERVE UNIVERSITY
Tendon Tissue Engineering by Electrochemically Aligned Collagen Bioscaffolds
  • 批准号：
    9089701
  • 项目类别：
  • 资助金额：
    $4.75万
  • 财政年份：
    2015
  • 负责人：
    Ozan Akkus
  • 依托单位：
    CASE WESTERN RESERVE UNIVERSITY
Tendon Tissue Engineering by Electrochemically Aligned Collagen Bioscaffolds
  • 批准号：
    8835033
  • 项目类别：
  • 资助金额：
    $32.64万
  • 财政年份：
    2014
  • 负责人：
    Ozan Akkus
  • 依托单位：
    CASE WESTERN RESERVE UNIVERSITY
Tendon Tissue Engineering by Electrochemically Aligned Collagen Bioscaffolds
  • 批准号：
    8697319
  • 项目类别：
  • 资助金额：
    $28.25万
  • 财政年份：
    2014
  • 负责人：
    Ozan Akkus
  • 依托单位：
    CASE WESTERN RESERVE UNIVERSITY
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