Translational Neuroscience Research in Alcoholism (TNRA-TP)

描述（由申请人提供）：这是T32培训计划的首次重新提交，即酒精中毒转化神经科学研究-培训计划（TNRA-TP），其目的是培训博士后学员弥合从基础科学研究中获得的知识应用到与酒精中毒相关的临床神经科学研究模型的差距。新一代的精神药理学、神经影像学和分子遗传学研究植根于分子神经科学，具有广泛的临床意义，这些研究带来了弥合基础和临床研究之间差距的潜力。TNRA-TP是一个为期两年的计划，在该部。耶鲁大学医学院精神病学系的研究生院，并将为博士后学员提供机会，在其职业生涯的初始阶段投入全职工作，以发展成为酗酒转化研究领域的独立研究人员所需的技能和经验。TNRA-TP包括三个核心项目，临床核心，神经影像认知神经科学核心和基础科学核心。TNRA-TP计划教师隶属于两个中心补助金（NIAAA资助的酒精中毒转化神经科学中心和VA资助的VA酒精研究中心），这两个中心都是多学科的，使该小组能够进行研究，从临床前项目（“工作台”）到临床研究（“床边”和“社区”）。申请人将是医学博士或博士博士后候选人，他们接受过精神病学、内科学、临床心理学或神经科学等专业的培训。候选人将根据他们在酗酒转化研究领域的卓越潜力进行选择。TNRA-TP计划包括1）个性化的研究指导，2）成功完成一个学术研究项目，3）核心课程（关于药物滥用临床研究和治疗，生物统计学和研究设计，科学研究的负责任行为和赠款写作技巧的研讨会）4）个性化参与部门感兴趣的研讨会，医学院和大学5）临床培训和6）教学培训。在培训结束时，申请人将非常适合在酗酒领域的翻译研究的独立职业。相关性（参见说明）：这个培训计划的目的是准备年轻的科学家（医学博士，博士）在酗酒领域的转化研究的职业生涯。

DESCRIPTION (provided by applicant): This is the first re-submission of a T32 training program, the Translational Neuroscience Research in Alcoholism- Training Program (TNRA-TP), the purpose of which is to train post-doctoral trainees in bridging the gap in the application of knowledge gained from basic science studies to clinical neuroscience research models related to alcoholism. A new generation of psychopharmacology, neuroimaging, and molecular genetic studies rooted in molecular neuroscience has broad clinical implications and these studies bring the potential to bridge the gap between basic and clinical research. TNRA-TP is a two-year program in the Dept. of Psychiatry, Yale University School of Medicine, and will afford post-doctoral trainees the opportunity to devote a full-time effort during the initial phase of their careers to developing the skills and experience needed to become independent researchers in the field of translational research in alcoholism. TNRA-TP includes three Core Programs, Clinical Core, Neuroimaging Cognitive Neuroscience Core, and Basic Science Core. The TNRA-TP program faculty are affiliated with two center grants (the NIAAA-funded Center for the Translational Neuroscience of Alcoholism and the VA-funded VA Alcohol Research Center), both of which are multi-disciplinary and enable the group to conduct research that moves rapidly and in both directions from preclinical projects ("bench") to clinical studies ("bedside" and "community"). Applicants will be MD's or PhD post-doctoral candidates trained in specialties that include psychiatry, internal medicine, clinical psychology or neuroscience. Candidates will be selected by their potential for excellence in the field of translational research in alcoholism. TNRA-TP program includes 1) individualized research preceptorship, 2) successful completion of a translational-research project, 3) a core curriculum (seminars on substance abuse clinical research and treatment, biostatistics and research design, the responsible conduct of scientific research and grant writing skills) 4) individualized participation in seminars of interest in the Depart, Medical School and University 5) clinical training and 6) training for teaching. At the conclusion of training, applicants will be well suited for independent careers in translational research in the field of alcoholism. RELEVANCE (See instructions): The purpose of this training program is to prepare young scientist (MD, PhD) for a career in translational research in the field of alcoholism.