Data Management, Analysis and Resources Dissemination Core (DMARD)

数据管理、分析和资源传播核心（DMARD）将支持所有四个方面。 通过提供快速、准确和具有成本效益的数据， 管理、高通量分析以及资源共享和传播 分享计划。DMARD核心职能将分为三个主要职责：资源共享， 全面的数据管理和基础设施，以支持高通量分析。我们的GCID 该计划将快速发布，预出版基因组和其他数据，包括元数据，详见 资源共享计划。原始基因组序列将尽快提交，不超过45 从生成和数据质量检查到跟踪存档或（如适用）到短 在NCBI/NLM/NIH上阅读存档。全基因组和部分基因组组装体将在NCB 1的GenBank中保存。 经核实后，不迟于45天内生成，随后发布到其他网站，如 经NIAID批准。单核苷酸多态性（SNP）作为该项目的一部分，将 尽快提交至NCBI dbSNP，且不迟于验证后45天。临床资料 和其他元数据将存放在适当的NIAID资助的生物信息学资源中心，或 其他适当的公共资源。通过NIAID GSC-BRC开发的元数据格式 将开展协作努力。JCVI GCID中使用的微生物菌株将存放在 NIAID BEI（生物防御和新兴感染研究资源库）或其他经批准的公共 储存库。在该计划内开发的信息学工具，用于处理或分析生成的数据 在执行该计划的研究项目的过程中，将被放置在公共领域，通过 SourceForge是开源的。DMARD将为跟踪提供全面的数据管理 元数据、样本、试剂和数据。DMARD将与技术核心合作，提供银河和 基于开普勒的模块化基础设施，用于综合分析和解释。DMARD将与 技术核心为研究社区提供随时可用的工具和管道。

The Data Management, Analysis and Resources Dissemination Core (DMARD) will support all four Research Projects and the Technology Core by providing rapid, accurate and cost-effective data management, high throughput analysis and resource sharing and dissemination according to the Resource Sharing Plan. DMARD Core functions will be divided into three primary responsibilities; resource sharing, comprehensive data management and infrastructure to support high throughput analysis. Our GCID Program will rapidly release, pre-publication genomic and other data including metadata as detailed in the Resource Sharing Plan. Raw genome sequence will be submitted as rapidly as possible not exceeding 45 days from generation and data quality check to either the Trace Archive or, as appropriate, to the Short Read Archive at NCBI/NLM/NIH. Full and partial genome assemblies will be deposited in GenBank at NCBl after verification, no later than 45 days of being generated, followed by release to other web sites, as approved by NIAID. Single nucleotide polymorphisms (SNP) generated as part of the project, will be submitted as rapidly as possible to NCBl dbSNP and not later than 45 days from validation. Clinical data and other metadata will be deposited to the appropriate NIAID funded Bioinformatics Resource Centers or other public resources as appropriate. Metadata formats developed through the NIAID GSC-BRC collaborative efforts will be employed. Microbial strains employed in the JCVI GCID will be deposited to the NIAID BEI (Biodefense & Emerging Infections Research Resources Repository) or other approved public repositories. Informatics tools developed within the Program for processing or analyzing the data generated in the course of performing the Program's Research Projects will be placed in the public domain via SourceForge as open source. The DMARD will provide comprehensive data management for tracking metadata, samples, reagents, and data. The DMARD will work with Technology Core to provide Galaxy and Kepler based modular infrastructure for integrative analysis and interpretation. The DMARD will work with the Technology Core to provide ready to use tools and pipelines to the research community.