Bioinformatics and Biotechnology Program

共享资源描述 生物信息学和生物技术共享资源提供了广泛的化学、生物分子和 支持癌症中心研究项目的生物信息学服务和专业知识。它包括 生物信息学、高通量DNA测序和基因分型、功能基因组学和蛋白质组学。 生物信息学为研究人员提供了访问高性能计算资源、生物信息学 软件，一个软件和数据库开发小组，以及10名博士级别的生物信息学专家。 高通量DNA测序和基因分型为研究人员提供了访问自动DMA的途径 序列分析、片段大小分析和SNP检测技术。功能基因组学提供 C DNA和Affymetrix微阵列为中心研究人员提供服务和分析。蛋白质组学提供了一系列 蛋白质化学能力，包括从凝胶切片或斑点识别蛋白质；从 通过LC-MS/MS、完整质量测量和2D-Gel分析对溶液进行分析。所有这些资源都是高度 使用我们基于Web的在线订购、跟踪、开具发票和数据检索，集成并易于访问 系统。目前共有68名全职员工，其中包括22名博士。S代表所有员工。 共享资源所包含的学科。

Description of Shared Resource The Bioinformatics & Biotechnology Shared Resource provides a broad range of chemistry, biomolecular, and bioinformatics services and expertise in support of Cancer Center research programs. It includes Bioinformatics, High-throughput DMA Sequencing & Genotyping, Functional Genomics, and Proteomics. Bioinformatics provides investigators with access to high-performance computing resources, bioinformatics software, a software and database development group, and a staff of 10 Ph.D.-level bioinformatics experts. High-throughput DNA Sequencing & Genotyping provides investigators with access to automated DMA sequence analysis, fragment size analysis, and SNP detection technologies. Functional Genomics provides cDNA and Affymetrix microarray services and analyses to Center investigators. Proteomics offers a range of protein chemistry capabilities including protein identification from a gel slice or spot; protein identification from a solution by LC-MS/MS; Intact mass measurement; and 2D-gel analysis. All of these resources are highly integrated and readily accessible using our Web-based on-line ordering, tracking, invoicing, and data retrieval system. In total, this shared resource staffing is now at 68 FTEs including 22 Ph.D.'s representing all disciplines encompassed by the Shared Resource.