Bioinformatics and Biotechnology Program

生物信息学和生物技术计划

• 批准号: 7714153
• 负责人: CLAYTON W. NAEVE
• 金额: $ 53.63万
• 依托单位: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-14 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7714153
• 关键词: Base Pairing; Bioinformatics; Bioinformatics Shared Resource; Biotechnology; Cancer Center; Cancer Center Support Grant; Capillary Electrophoresis; Chemistry; Childhood; Complementary DNA; Computer software; DNA; DNA Microarray Chip; DNA Microarray format; DNA Sequence; DNA Sequence Analysis; Data; Data Storage and Retrieval; Databases; Detection; Development; Discipline; Disease; Doctor of Philosophy; Environment; Ependymoma; Funding; Gel; Genome; Genotype; High Performance Computing; Internet; Laboratories; Malignant Neoplasms; Measurement; Methylation; Mission; NCI Center for Cancer Research; Oligonucleotides; Online Systems; Operative Surgical Procedures; Performance; Postdoctoral Fellow; Process; Production; Protein Chemistry; Proteins; Proteomics; Purpose; Range; Rate; Research Personnel; Resource Sharing; Resources; Robotics; Saint Jude Children' s Research Hospital; Science; Security; Seminal; Sequence Analysis; Services; Slice; Solutions; Spottings; System; Technology; base; computing resources; data management; functional genomics; instrumentation; medulloblastoma; programs; size; software development

Description of Shared Resource The Bioinformatics & Biotechnology Shared Resource provides a broad range of chemistry, biomolecular, and bioinformatics services and expertise in support of Cancer Center research programs. It includes Bioinformatics, High-throughput DMA Sequencing & Genotyping, Functional Genomics, and Proteomics. Bioinformatics provides investigators with access to high-performance computing resources, bioinformatics software, a software and database development group, and a staff of 10 Ph.D.-level bioinformatics experts. High-throughput DNA Sequencing & Genotyping provides investigators with access to automated DMA sequence analysis, fragment size analysis, and SNP detection technologies. Functional Genomics provides cDNA and Affymetrix microarray services and analyses to Center investigators. Proteomics offers a range of protein chemistry capabilities including protein identification from a gel slice or spot; protein identification from a solution by LC-MS/MS; Intact mass measurement; and 2D-gel analysis. All of these resources are highly integrated and readily accessible using our Web-based on-line ordering, tracking, invoicing, and data retrieval system. In total, this shared resource staffing is now at 68 FTEs including 22 Ph.D.'s representing all disciplines encompassed by the Shared Resource.

共享资源描述 生物信息学和生物技术共享资源提供了广泛的化学，生物分子， 生物信息学服务和专业知识，以支持癌症中心的研究计划。它包括 生物信息学、高通量DNA测序和基因分型、功能基因组学和蛋白质组学。 生物信息学为研究人员提供了访问高性能计算资源， 软件，一个软件和数据库开发小组，以及10名博士-生物信息学专家。 高通量DNA测序和基因分型为研究人员提供了自动化DMA 序列分析、片段大小分析和SNP检测技术。功能基因组学提供 cDNA和Affymetrix微阵列为中心研究人员提供服务和分析。蛋白质组学提供了一系列 蛋白质化学能力，包括从凝胶切片或斑点进行蛋白质鉴定; 通过LC-MS/MS测定溶液;完整质量测量;和2D-凝胶分析。所有这些资源都是高度 通过我们基于Web的在线订购、跟踪、开票和数据检索， 系统目前共有68名全职员工，包括22名博士。代表着 共享资源所包含的学科。