Translational Biology Core

转化生物学核心

• 批准号: 8935196
• 负责人: DARRON R BROWN
• 金额: $ 9.55万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-19 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8935196
• 关键词: Acquired Immunodeficiency Syndrome; Africa South of the Sahara; American; Biology; Biopsy; Biostatistics Core; Cancerous; Cervical; Cervical Intraepithelial Neoplasia; Cervical dysplasia; Chlamydia trachomatis; Cold Therapy; Data; Development; Diagnosis; Educational process of instructing; Epidemiology; Future; Genotype; HIV; Head and Neck Cancer; Health Services Accessibility; Human Papillomavirus; Human papilloma virus infection; Incidence; Indiana; Infection; Institutes; Kenya; Knowledge; Laboratories; Life; Loop electrosurgical excision procedure; Malignant Neoplasms; Malignant Vaginal Neoplasm; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Malignant neoplasm of vulva; Medical Research; Mentors; Modeling; Molecular Epidemiology; Neisseria gonorrhoeae; Oncogenic; Physicians; Prevention; Principal Investigator; Process; Research Institute; Research Personnel; Risk; Role; Sampling; Scientist; Sexually Transmitted Diseases; Site; Students; Swab; Testing; Transportation; Universities; Vagina; Woman; biobank; burden of illness; data management; experience; graduate student; medical schools; oncology

Translational Biology Core The objective of the Translational Biology Core (TBC) is to provide support to Projects 1 ("Modifiable factors predicting persistence of oncogenic HPV and cervical dysplasia in HIV-positive Kenyan women") and Project 2 ("Results of Cryotherapy/LEEP among HIV- and HIV+ Women in Western Kenya") of the AMPATH-Oncology Institute: HPV and Cervical Cancer in Kenyan Women with HIV/AIDS. This support will include storage of samples, transportation of samples between testing sites, STI testing, HPV genotyping, and providing a space in which young physician scientists, graduate students, and technicians can expand their laboratory repertoire. The division of labor will occur between two sites: 1) Academic Model Providing Access to Healthcare (AMPATH) in partnership with the Moi University School of Medicine (MUSOM) in Eldoret, Kenya and 2) Kenya Medical Research Institute (KEMRI) in Kisumu, Kenya. Both laboratories have unique capabilities that will be integrated to provide the testing necessary to complete these projects outlined in this proposal. The other role of the TBC is to interact with the Mentoring Core (MC) and the Biostatistics Core and Data Management (BC). The TBC will be generating the data that will be further analyzed by the BC and will regularly collaborate with them. The TBC will also provide the space for teaching trainees that will be guided by the MC.

翻译生物学核心