University of Washington GI Training Grant

华盛顿大学退伍军人培训补助金

• 批准号: 8728801
• 负责人: JOHN MATTHEW INADOMI
• 金额: $ 16.38万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-06 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8728801
• 关键词: Grant; Training; Universities; Washington

DESCRIPTION (provided by applicant): The University of Washington School of Medicine serves as the sole medical educational resource for 5 states in the US Northwest: Washington, Wyoming, Alaska, Montana, and Idaho. It is also recognized as a major institution in biomedical research; since 1974, UW ranks first amongst American public universities for federal research funding and second amongst all universities (public and private) since 1991 for competing federal science and engineering grants. Within the UW, the Division of Gastroenterology of the Department of Medicine, composed of a core of 36 full-time faculty members, operates from five medical centers: the University of Washington Health Sciences Center, the Veterans Affairs Puget Sound Health Care System, the Harborview Medical Center, the Seattle Cancer Care Alliance/Fred Hutchinson Cancer Research Center, and Pacific Medical Clinics. This diversity allows the research and clinical programs of the GI Division to benefit from complementary strengths, ranging from tertiary referral centers to primary care centers in urban or rural setting, and from highly specialized centers to broadly diversified county medical centers. Benefiting from these strengths, the GI Division has had a long tradition of training academic fellows, dating to the 1950's. This application requests two trainees per year who will undergo rigorous research training for two year (4 positions total). SPECIFIC AIMS: Our training program has two specific aims that are integrated through our clinical and translational research infrastructure: . Translational Research in Gastrointestinal and Liver Disease 2. Epidemiology, Outcomes & Health Services Research. We propose multidisciplinary research between our specific aims spanning the definition of translational research. Specifically, the research infrastructure to conduct research using biological samples linked with baseline clinical data and long-term follow-up of clinical outcomes has been constructed in the Division of Gastroenterology as a means to allow "every patient to participate in research." This infrastructure will allow us to develop cohorts of patients that are categorized with regards to clinical risk factors and biological parameters and follow them to observe clinical outcomes including disease incidence, morbidity and mortality. It is the availability of these clinically and biologically characterized cohorts with longitudinal follow-up that distinguish our program from others.

描述（由申请人提供）：华盛顿大学医学院是美国西北部 5 个州的唯一医学教育资源：华盛顿州、怀俄明州、阿拉斯加州、蒙大拿州和爱达荷州。它也被认为是生物医学研究的主要机构；自 1974 年以来，华盛顿大学在联邦研究经费方面在美国公立大学中排名第一，自 1991 年以来在竞争性联邦科学和工程经费方面在所有大学（公立和私立）中排名第二。在华盛顿大学内，医学系胃肠病学部由 36 名全职教员组成，下属五个医疗中心：华盛顿大学健康科学中心、退伍军人事务部普吉特湾医疗保健系统、Harborview 医疗中心、西雅图癌症护理联盟/弗雷德·哈钦森癌症研究中心和太平洋医疗诊所。这种多样性使得 GI 部门的研究和临床项目能够受益于互补优势，从三级转诊中心到城市或农村的初级保健中心，从高度专业化的中心到广泛多元化的县医疗中心。 受益于这些优势，GI 部门拥有培训学术研究员的悠久传统，其历史可以追溯到 1950 年代。该申请每年要求两名实习生，他们将接受为期两年的严格研究培训（总共 4 个职位）。具体目标：我们的培训计划有两个具体目标，这些目标通过我们的临床和转化研究基础设施进行整合：胃肠道和肝脏疾病的转化研究 2. 流行病学、结果和健康服务研究。我们建议在跨越转化研究定义的具体目标之间进行多学科研究。具体而言，消化科已构建了利用与基线临床数据相关的生物样本进行研究和长期跟踪临床结果的研究基础设施，作为让“每个患者参与研究”的手段。该基础设施将使我们能够开发根据临床风险因素和生物学参数进行分类的患者队列，并跟踪他们观察临床结果，包括疾病发生率、发病率和死亡率。正是这些具有临床和生物学特征的队列的可用性以及纵向随访使我们的项目与其他项目区分开来。