NIDDK Biosample Repository

NIDDK 生物样本库

• 批准号: 8853996
• 负责人: HEATHER HIGGINS
• 金额: $ 221.56万
• 依托单位: FISHER BIOSERVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8853996
• 关键词: Advanced Development; Algorithms; Clinical; Clinical Research; Collaborations; Collection; Contracts; Disease; Ensure; Ethics; Funding; Future; Institutes; Internal Medicine; Mission; National Institute of Diabetes and Digestive and Kidney Diseases; Participant; Patients; Process; Prognostic Marker; Qualifying; Research; Research Personnel; Resources; Sampling; Specific qualifier value; Therapeutic; United States National Institutes of Health; Work; cost effective; novel strategies; repository

"The NIDDK conducts and supports much of the clinical research on the diseases of internal medicine and related subspecialty fields. Many of the large clinical studies funded by the NIDDK collect biospecimens from subjects for analysis and future study. The collection of these patient and control samples from many different studies in a single repository is a valuable resource with which researchers can rapidly validate clinical hypotheses and algorithms for clinical decision. The collection is also advancing the development of prognostics, markers, and therapeutics for diseases related to the mission of the NIDDK. This project, which will be referred to herein as “the Biosample Repository”, continues an important collection begun in 2003 and is conceptually related to repositories in existence at other institutes at the NIH. The repository stores and maintains biosamples under high quality conditions, and distributes them in an equitable and ethical manner. This facilitates sharing of NIDDK-supported resources, thus encouraging work by junior investigators, investigators with novel approaches, and others not included in current collaborations, without excluding those who are established in their fields. It helps to ensure that research participants make a maximal contribution, and decreases duplicative sampling efforts."

“NIDDK进行和支持许多关于内科疾病和相关专科领域的临床研究。许多由NIDDK资助的大型临床研究从受试者中收集生物标本进行分析和未来研究。将来自许多不同研究的这些患者和对照样本收集在一个存储库中是一种宝贵的资源，研究人员可以利用它快速验证临床假设和临床决策算法。该系列还推动了与NIDDK使命相关的疾病的免疫学、标志物和治疗方法的发展。该项目在本文中将被称为“生物样品储存库”，它延续了2003年开始的重要收集工作，在概念上与NIH其他研究所现有的储存库有关。 该储存库以高质量的条件储存和维护生物样本，并以公平和道德的方式分发这些样本。这有助于共享NIDDK支持的资源，从而鼓励初级研究人员、采用新方法的研究人员和其他未包括在当前合作中的人员开展工作，但不排除在各自领域已确立地位的人员。它有助于确保研究参与者做出最大贡献，并减少重复抽样工作。"