NIDDK Central Repositories-Biosample

NIDDK 中央存储库-Biosample

• 批准号: 8443770
• 负责人: HEATHER HIGGINS
• 金额: $ 107.25万
• 依托单位: FISHER BIOSERVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8443770
• 关键词: Advanced Development; Algorithms; Clinical; Clinical Research; Collaborations; Collection; Contracts; Disease; Ensure; Ethics; Funding; Future; Institutes; Internal Medicine; Mission; National Institute of Diabetes and Digestive and Kidney Diseases; Participant; Patients; Process; Prognostic Marker; Qualifying; Research; Research Personnel; Resources; Sampling; Specific qualifier value; Therapeutic; United States National Institutes of Health; Work; cost effective; novel strategies; repository

The NIDDK conducts and supports much of the clinical research on the diseases of internal medicine and related subspecialty fields. Many of the large clinical studies funded by the NIDDK collect biospecimens from subjects for analysis and future study. The collection of these patient and control samples from many different studies in a single repository is a valuable resource with which researchers can rapidly validate clinical hypotheses and algorithms for clinical decision. The collection is also advancing the development of prognostics, markers, and therapeutics for diseases related to the mission of the NIDDK. This project, which will be referred to herein as ¿the Biosample Repository¿, continues an important collection begun in 2003 and is conceptually related to repositories in existence at other institutes at the NIH. The repository stores and maintains biosamples under high quality conditions, and distributes them in an equitable and ethical manner. This facilitates sharing of NIDDK-supported resources, thus encouraging work by junior investigators, investigators with novel approaches, and others not included in current collaborations, without excluding those who are established in their fields. It helps to ensure that research participants make a maximal contribution, and decreases duplicative sampling efforts.

NIDDK 开展并支持内科疾病和相关亚专业领域的大部分临床研究。 NIDDK 资助的许多大型临床研究都会从受试者身上收集生物样本以供分析和未来研究。将来自许多不同研究的这些患者和对照样本收集在一个存储库中是一种宝贵的资源，研究人员可以利用它快速验证临床假设和临床决策算法。该集合还推动与 NIDDK 使命相关的疾病的预后、标记物和治疗方法的开发。该项目在本文中被称为“生物样本存储库”，延续了 2003 年开始的重要收集工作，并且在概念上与 NIH 其他研究所现有的存储库相关。 该存储库在高质量条件下存储和维护生物样本，并以公平和道德的方式分配它们。这有助于共享 NIDDK 支持的资源，从而鼓励初级研究人员、采用新颖方法的研究人员以及其他未包含在当前合作中的研究人员的工作，而不排除那些在各自领域建立的人。它有助于确保研究参与者做出最大贡献，并减少重复抽样工作。