Neuroimaging Core

神经影像核心

• 批准号: 8690123
• 负责人: EINAR MENCL
• 金额: $ 16.11万
• 依托单位: HASKINS LABORATORIES, INC.
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8690123
• 关键词: Automation; Boxing; Code; Communication; Competence; Computer software; Computers; Data; Data Analyses; Development; Electroencephalography; Event-Related Potentials; Fostering; Functional Magnetic Resonance Imaging; Goals; Housing; Human Resources; Image; Instruction; Laboratories; Language; Life; Linux; Magnetic Resonance Imaging; Medical; Methodology; Nature; Near-Infrared Spectroscopy; Neuroanatomy; Neurobiology; Outcome; Persons; Physics; Postdoctoral Fellow; Procedures; Process; Program Efficiency; Quality Control; Research Personnel; Resources; Running; Scientist; Site; Speech; Standardization; Techniques; Testing; Training; Writing; computerized data processing; data acquisition; design; imaging modality; meetings; neuroimaging; programs; research study; response

The Neuroimaging Core (Core B, NC) will provide expertise and support for acquisition and analysis of structural and functional Magnetic Resonance Imaging (sMRI/fMRI), functional Near-Infrared Spectroscopy (NIRS), and electroencephalography/event related potentials (EEG/ERP). By providing a centralized organizatlon for use of these techniques across multiple Projects, the NC will greatly increase efficiency of the Program as a whole by eliminating redundancy and providing common processing procedures and automation. Further, it will enable comparability across Projects and sites, by providing standardization in acquisition and analysis. The speciflc strengths of the Core Director and Invesflgators support each methodology: key personnel include experts Dr. Einar Mend, Core Director (structural and funcflonal MRI); Dr. Nicole Landi (EEG/ERP); and Heather Bortfeld (NIRS). Select consultants provide additional expertise: Dr. Robert Fulbright (neuroanatomy and medical review); Dr. Todd Constable (MR physics); and Dr. Ching-Po Lin (flbertract.imaging using DTI and DSI). Computaflonal resources are extensive, including multiple Linux and PC boxes, and a 40-core Mac Xgrid network running all necessary MR software packages and in-house developed Maflab programs. ERP and NIRS data processing are supported by dedicated Macintosh Pro computers. The NC will maintain wikis for communication and QC across sites, and provide local (weekly in person) and global (monthly via Skype) meetings for relevant staff and scientists. The NC will instantiate and maintain quality control and comparability of data acquisitions within each technique, across the multiple sites. As needed, NC staff will provide training of scientists and research associates across Projects in data acquisition and analysis. The NC will provide support for the proper design of experiments to take advantage of the particular strengths of each imaging modality. NC staff will preprocess and perform initial subject-level analysis for all MRI data collected at Haskins Laboratories, and provide support to Project scientists performing main across-subjects analyses for hypothesis testing. Finally, the NC staff will actively develop new techniques for acquisition and analysis to support the scientific goals of the Project.

神经成像核心（Core B， NC）将为结构和功能磁共振成像（sMRI/fMRI）、功能近红外光谱（NIRS）和脑电图/事件相关电位（EEG/ERP）的采集和分析提供专业知识和支持。通过为跨多个项目使用这些技术提供一个集中的组织，NC将通过消除冗余并提供通用的加工程序和自动化，大大提高整个程序的效率。此外，通过提供获取和分析的标准化，它将支持跨项目和站点的可比性。核心主任和研究人员的具体优势支持每种方法：主要人员包括专家，核心主任Einar Mend博士（结构和功能MRI）；Nicole Landi博士（EEG/ERP）；希瑟·波特菲尔德（NIRS）。精选顾问提供额外的专业知识：Robert Fulbright博士（神经解剖学和医学评论）；Todd Constable博士（磁共振物理）；林庆宝博士（flbertract）。DTI和DSI成像)。计算资源是广泛的，包括多个Linux和PC机，以及运行所有必要的MR软件包和内部开发的Maflab程序的40核Mac Xgrid网络。ERP和NIRS数据处理由专用的Macintosh Pro计算机支持。NC将维护跨站点通信和质量控制的wiki，并为相关工作人员和科学家提供本地（每周亲自）和全球（每月通过Skype）会议。NC将实例化和维护质量控制和数据采集的可比性，在每个技术中，跨越多个站点。根据需要，NC工作人员将为科学家和研究人员提供培训