Neuroimaging Core

神经成像核心(核心B，北卡罗来纳州)将为结构和功能磁共振成像(sMRI/fMRI)、功能近红外光谱(NIRS)和脑电/事件相关电位(EEG/ERP)的获取和分析提供专业知识和支持。通过为在多个项目中使用这些技术提供一个集中的组织，NC将通过消除冗余并提供通用的处理程序和自动化来极大地提高整个计划的效率。此外，它将通过在获取和分析方面提供标准化，实现项目和地点之间的可比性。核心总监和发起人的专业能力支持每种方法：关键人员包括专家，核心总监(结构和功能磁共振)Eina Mend博士，Nicole Landi博士(脑电/ERP)和Heather Bortfeld(NIRS)。精选的顾问提供额外的专业知识：Robert Fulbright博士(神经解剖学和医学回顾)；Todd Conable博士(MR物理学)；以及Ching-Po Lin博士(flbertra。使用DTI和DSI进行成像)。Computaflonal资源广泛，包括多个Linux和PC机顶盒，以及运行所有必要的MR软件包和内部开发的MafLab程序的40核Mac Xgrid网络。企业资源规划和近红外数据处理由专用的Macintosh Pro计算机支持。全国委员会将维护用于跨地点沟通和质量控制的Wiki，并为相关工作人员和科学家提供本地(每周面对面)和全球(每月通过Skype)会议。NC将实例化并维护跨多个站点的每项技术内的数据采集的质量控制和可比性。根据需要，北卡罗来纳州的工作人员将为科学家和研究助理提供培训 数据采集和分析方面的项目。该中心将为实验的适当设计提供支持，以利用每种成像方式的特殊优势。NC工作人员将对哈斯金斯实验室收集的所有核磁共振数据进行预处理和初步的主题级别分析，并为项目科学家执行主要的跨主题分析以进行假设检验提供支持。最后，NC工作人员将积极开发新的采集和分析技术，以支持项目的科学目标。

The Neuroimaging Core (Core B, NC) will provide expertise and support for acquisition and analysis of structural and functional Magnetic Resonance Imaging (sMRI/fMRI), functional Near-Infrared Spectroscopy (NIRS), and electroencephalography/event related potentials (EEG/ERP). By providing a centralized organizatlon for use of these techniques across multiple Projects, the NC will greatly increase efficiency of the Program as a whole by eliminating redundancy and providing common processing procedures and automation. Further, it will enable comparability across Projects and sites, by providing standardization in acquisition and analysis. The speciflc strengths of the Core Director and Invesflgators support each methodology: key personnel include experts Dr. Einar Mend, Core Director (structural and funcflonal MRI); Dr. Nicole Landi (EEG/ERP); and Heather Bortfeld (NIRS). Select consultants provide additional expertise: Dr. Robert Fulbright (neuroanatomy and medical review); Dr. Todd Constable (MR physics); and Dr. Ching-Po Lin (flbertract.imaging using DTI and DSI). Computaflonal resources are extensive, including multiple Linux and PC boxes, and a 40-core Mac Xgrid network running all necessary MR software packages and in-house developed Maflab programs. ERP and NIRS data processing are supported by dedicated Macintosh Pro computers. The NC will maintain wikis for communication and QC across sites, and provide local (weekly in person) and global (monthly via Skype) meetings for relevant staff and scientists. The NC will instantiate and maintain quality control and comparability of data acquisitions within each technique, across the multiple sites. As needed, NC staff will provide training of scientists and research associates across Projects in data acquisition and analysis. The NC will provide support for the proper design of experiments to take advantage of the particular strengths of each imaging modality. NC staff will preprocess and perform initial subject-level analysis for all MRI data collected at Haskins Laboratories, and provide support to Project scientists performing main across-subjects analyses for hypothesis testing. Finally, the NC staff will actively develop new techniques for acquisition and analysis to support the scientific goals of the Project.