The Challenge of Individualizing Treatments for Patients with Breast Cancer
乳腺癌患者个体化治疗的挑战
基本信息
- 批准号:8726338
- 负责人:
- 金额:$ 291.47万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-09-01 至 2017-08-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAttitudeBreastBreast Cancer TreatmentCancer PatientCaringCatchment AreaClinicalCommunicationDataData CollectionDecision MakingDiagnosisDiseaseDisease-Free SurvivalEffectivenessEvaluationFaceGoalsIndividualInterdisciplinary StudyInternetInterventionKnowledgeLeftMalignant NeoplasmsMedical OncologistMedicineMethodologyMethodsMissionMorbidity - disease rateNew JerseyNewly DiagnosedObservational StudyOutcomeOutcomes ResearchPainPatient RightsPatientsPhysiciansPopulationPopulation SciencesProcessPublic HealthRandomized Controlled TrialsRegistriesReportingResearchResource SharingSamplingSeasonsStrategic PlanningSurgeonSurveysSystemic TherapyTestingTranslational ResearchWomanWorkbasecancer carecancer therapydesignevidence baseimprovedinnovationmalignant breast neoplasmmetropolitanoncologyoutcome forecastpopulation basedpopulation healthpreferenceprogramsscreeningtooltreatment strategy
项目摘要
DESCRIPTION (provided by applicant): Treatments for cancer impose substantial burden and morbidity but net survival benefit of different strategies is often small and virtually always uncertain. Thus, clinicians may do more harm than good if treatment is too aggressive. There are a number of management strategies for breast cancer aimed at reducing unnecessary morbidity and burden on patients with favorable disease. A key barrier to advancing these initiatives is the need for a better understanding of the challenges of individualizing cancer care The goal of this program is to improve population health by helping clinicians and their patients address the challenges of individualizing treatment of breast cancer for patients with favorable prognosis. Objective 1: To examine the challenges of individualizing treatment for women with breast cancer. Two projects will each undertake an observational study of patients newly diagnosed with breast cancer (including their attending clinicians) who were reported to the SEER registries of Georgia and New Jersey during an 18 month period to examine patient and clinician factors associated with key evaluative tests, treatments, and patient appraisal of decision quality. Project 1 will focus on challenges for surgeons and their patients with regard to locoregional therapy. Project 2 will focus on challenges for medical oncologists and their patients with regard to systemic therapy. Objective 2: To improve treatment decision quality. Project 3 will perform a randomized controlled trial of a practice based online decision tool for patients newly diagnosed with breast cancer in the Detroit and Atlanta SEER regions intended to improve decision quality. Objective 3: To accelerate the dissemination of SEER-based research findings by implementing and evaluating a tailored online portal aimed at all surgeons and medical oncologists who treated the patient samples in P1 and P2 to evaluate whether our research findings can more directly and promptly inform clinicians knowledge and attitudes about individualizing treatment. Objective 4: To advance methods in SEER population translational research focused on quality of cancer care. We propose four shared resource cores that will support program project activities, advance innovative methods in oncology population sciences, and advance team mission and long-term strategic planning.
描述(由申请人提供):癌症治疗会造成巨大的负担和发病率,但不同策略的净生存获益往往很小,而且几乎总是不确定的。因此,如果治疗过于激进,临床医生可能弊大于利。有许多乳腺癌的管理策略,旨在减少不必要的发病率和对患者的负担有利的疾病。推进这些举措的一个关键障碍是需要更好地了解个性化癌症护理的挑战。该计划的目标是通过帮助临床医生及其患者解决预后良好的乳腺癌患者个性化治疗的挑战来改善人群健康。目的1:探讨女性乳腺癌个体化治疗的挑战。两个项目将分别对新诊断为乳腺癌的患者(包括其主治医生)进行一项观察性研究,这些患者在18个月期间报告给格鲁吉亚和新泽西的SEER登记处,以检查与关键评价性检测、治疗和患者决策质量评估相关的患者和临床医生因素。项目1将重点关注外科医生及其患者在局部治疗方面面临的挑战。项目2将重点关注肿瘤内科医生及其患者在系统治疗方面面临的挑战。目的2:提高治疗决策质量。项目3将对底特律和亚特兰大SEER地区新诊断为乳腺癌的患者进行基于实践的在线决策工具的随机对照试验,旨在提高决策质量。目标三:通过实施和评估针对所有在P1和P2中治疗患者样本的外科医生和医学肿瘤学家的定制在线门户网站,以加速基于SEER的研究结果的传播,以评估我们的研究结果是否可以更直接,更及时地告知临床医生关于个性化治疗的知识和态度。目标4:推进SEER人群转化研究的方法,重点关注癌症护理质量。我们提出了四个共享资源核心,将支持计划项目活动,推进肿瘤学人口科学的创新方法,以及推进团队使命和长期战略规划。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Steven J. Katz其他文献
Studies on the ring opening reactions of 3-oxa-1-azabicyclo(3.1.0)hexan-2-ones. Synthesis of aminomethyl oxazolidinones and aziridinyl ureas
3-氧杂-1-氮杂双环(3.1.0)己-2-酮的开环反应研究。
- DOI:
- 发表时间:
2012 - 期刊:
- 影响因子:0
- 作者:
G. Wells;T. Dudding;Lee Belding;J. Frick;Abhijit Nayek;Junfeng Huang;Steven J. Katz;S. Bergmeier - 通讯作者:
S. Bergmeier
Healthy behaviors among women in the United States and Ontario: the effect on use of preventive care.
美国和安大略省妇女的健康行为:对使用预防性护理的影响。
- DOI:
- 发表时间:
1996 - 期刊:
- 影响因子:12.7
- 作者:
Timothy P. Hofer;Steven J. Katz - 通讯作者:
Steven J. Katz
COVID-19 information uptake amongst a rheumatology interested population
- DOI:
10.1007/s10067-023-06571-2 - 发表时间:
2023-03-09 - 期刊:
- 影响因子:2.800
- 作者:
Steven J. Katz;Jill J. Hall - 通讯作者:
Jill J. Hall
Syndrome de défaillance des barorécepteurs après chirurgie bilatérale pour tumeurs glomiques carotidiennes
颈动脉瘤双边手术后压力感受器失效综合征
- DOI:
10.1016/j.acvfr.2011.05.016 - 发表时间:
2010 - 期刊:
- 影响因子:0
- 作者:
Ilia Gur;Steven J. Katz - 通讯作者:
Steven J. Katz
Sampling and methods of the European Study of the Epidemiology of Mental Disorders (ESEMeD) project
欧洲精神障碍流行病学研究 (ESEMeD) 项目的抽样和方法
- DOI:
10.1111/j.1600-0047.2004.00326 - 发表时间:
2004 - 期刊:
- 影响因子:6.7
- 作者:
J. Alonso;M. Angermeyer;S. Bernert;R. Bruffaerts;Terry Brugha;H. Bryson;G. Girolamo;R. Graaf;K. Demyttenaere;I. Gasquet;J. Haro;Steven J. Katz;R. C. Kessler;V. Kovess;J. Lépine;J. Ormel;G. Polidori;L. Russo;G. Vilagut;J. Almansa;S. Arbabzadeh;J. Autonell;M. Bernal;M. Buist;M. Codony;A. Domingo;Montserrat Ferrer;S. Joo;M. Martinez;H. Matschinger;F. Mazzi;Z. Morgan;P. Morosini;C. Palacín;B. Romera;Nick Taub;W. Vollebergh;ESEMeD - 通讯作者:
ESEMeD
Steven J. Katz的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Steven J. Katz', 18)}}的其他基金
The Challenge of Individualizing Treatments for Patients with Breast Cancer
乳腺癌患者个体化治疗的挑战
- 批准号:
8539482 - 财政年份:2012
- 资助金额:
$ 291.47万 - 项目类别:
The Challenge of Individualizing Treatments for Patients with Breast Cancer
乳腺癌患者个体化治疗的挑战
- 批准号:
8340091 - 财政年份:2012
- 资助金额:
$ 291.47万 - 项目类别:
Quality of Cancer Care Evaluation and Interventions
癌症护理质量评估和干预措施
- 批准号:
7921300 - 财政年份:2009
- 资助金额:
$ 291.47万 - 项目类别:
Quality of Cancer Care Evaluation and Interventions
癌症护理质量评估和干预措施
- 批准号:
7925637 - 财政年份:2006
- 资助金额:
$ 291.47万 - 项目类别:
Quality of Cancer Care Evaluation and Interventions
癌症护理质量评估和干预措施
- 批准号:
7289258 - 财政年份:2006
- 资助金额:
$ 291.47万 - 项目类别:
Quality of Cancer Care Evaluation and Interventions
癌症护理质量评估和干预措施
- 批准号:
7096860 - 财政年份:2006
- 资助金额:
$ 291.47万 - 项目类别:
Quality of Cancer Care Evaluation and Interventions
癌症护理质量评估和干预措施
- 批准号:
8138475 - 财政年份:2006
- 资助金额:
$ 291.47万 - 项目类别:
Quality of Cancer Care Evaluation and Interventions
癌症护理质量评估和干预措施
- 批准号:
7500175 - 财政年份:2006
- 资助金额:
$ 291.47万 - 项目类别:
Breast Cancer Treatment Decisions & Outcomes in Latinas
乳腺癌治疗决策
- 批准号:
6941367 - 财政年份:2004
- 资助金额:
$ 291.47万 - 项目类别:
相似海外基金
STTR Phase I: A Reliable and Efficient New Method for Satellite Attitude Control
STTR第一阶段:可靠、高效的卫星姿态控制新方法
- 批准号:
2310323 - 财政年份:2024
- 资助金额:
$ 291.47万 - 项目类别:
Standard Grant
BCSER - PVEST: A Dynamic Framework for Investigating STEM Interest, Attitude and Identity Among African American Middle School Students
BCSER - PVEST:调查非裔美国中学生 STEM 兴趣、态度和身份的动态框架
- 批准号:
2327055 - 财政年份:2023
- 资助金额:
$ 291.47万 - 项目类别:
Standard Grant
The hidden power of grammar: a mixed-methods study of media discourses on climate change protests and their effects on audience attitude.
语法的隐藏力量:气候变化抗议媒体话语及其对受众态度影响的混合方法研究。
- 批准号:
2881735 - 财政年份:2023
- 资助金额:
$ 291.47万 - 项目类别:
Studentship
Development of Psychological Approach to Improve Intergroup Attitude and Behavior and Exploration of Its Application
改善群际态度和行为的心理学方法的发展及其应用探索
- 批准号:
23K12855 - 财政年份:2023
- 资助金额:
$ 291.47万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Attitude and Identity in Wales' Primary and Secondary Schools
威尔士中小学的态度和认同
- 批准号:
2876788 - 财政年份:2023
- 资助金额:
$ 291.47万 - 项目类别:
Studentship
Attitude and Shape Estimation of an Unknown Object Using Light Curves
使用光曲线估计未知物体的姿态和形状
- 批准号:
23K04232 - 财政年份:2023
- 资助金额:
$ 291.47万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Examining the relationship between death attitude and AD completion and attitude among older Chinese Americans
研究老年华裔美国人的死亡态度与 AD 完成度和态度之间的关系
- 批准号:
10575699 - 财政年份:2023
- 资助金额:
$ 291.47万 - 项目类别:
Insect flight mechanisms in high flight attitude
高飞行姿态下昆虫的飞行机制
- 批准号:
22H01397 - 财政年份:2022
- 资助金额:
$ 291.47万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
High-accurate relative position and rotation control of multiple satellites considering orbit-attitude coupled dynamics for space interferometry
空间干涉测量中考虑轨道姿态耦合动力学的多卫星高精度相对位置和旋转控制
- 批准号:
22K18856 - 财政年份:2022
- 资助金额:
$ 291.47万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Solar Sailing: Attitude, Orbit, and Shape Control
太阳航行:姿态、轨道和形状控制
- 批准号:
RGPIN-2020-04037 - 财政年份:2022
- 资助金额:
$ 291.47万 - 项目类别:
Discovery Grants Program - Individual