Tamburro Symposium on Environmental Chemicals and Liver Disease

Tamburro 环境化学物质与肝病研讨会

• 批准号: 8785871
• 负责人: Matthew C Cave
• 金额: $ 1.54万
• 依托单位: UNIVERSITY OF LOUISVILLE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8785871
• 关键词: Adult; Affect; Chemical Industry; Chemicals; Child; Cirrhosis; Clinical; Clinical Sciences; Communities; Complex; Data; Discipline; Energy Metabolism; Environmental Exposure; Environmental Health; Environmental Pollutants; Epidemic; Extramural Activities; Faculty; Female; Fibrosis; Fostering; Geographic Locations; Goals; Government; Hepatic; Hepatitis; Hepatology; Hepatotoxicity; Individual; Industry; Journals; Knowledge; Lesion; Liver; Liver diseases; Malignant - descriptor; Malignant neoplasm of liver; Medical; Medical Education; Medical Students; Metabolism; Minority; National Institute of Environmental Health Sciences; Non-Malignant; Nutritional; Occupational; Organ; Outcome; Participant; Pathologic; Patient Care; Peer Review; Physicians; Play; Prevalence; Publishing; Recording of previous events; Recruitment Activity; Research; Research Personnel; Resources; Role; Scientist; Site; Staging; Students; Toxic Environmental Substances; Toxicity Tests; Translational Research; Universities; Veterinarians; Woman; Workplace; Xenobiotic Metabolism; chronic liver disease; design; environmental chemical; environmental chemical exposure; experience; graduate student; interest; lectures; liver injury; meetings; new technology; nutrition; population based; posters; professor; public health relevance; response; symposium; toxicant

DESCRIPTION (provided by applicant) The liver is the largest internal organ and also the most complex as it regulates xenobiotic and energy metabolism. However, liver disease is increasingly common, and current population-based studies indicate that greater than 1/3 of adults and greater than 10% of children have chronic liver disease. Presumably due to its role in xenobiotic metabolism, the liver is the target organ most commonly affected by environmental chemicals. However, the role of environmental exposures in the current liver disease epidemic is simultaneously under-recognized by clinicians and understudied by the scientific research community. The primary objective of this application is to hold a two-day symposium on "Environmental Chemicals and Liver Disease". There have been no comprehensive conferences in the last five years (if ever) on the emerging field of environmental hepatology. An expert panel of faculty participants has been recruited and 26 lectures and a poster session are planned. Notably, faculty participants with diverse professional backgrounds (ranging from clinical hepatologists to environmental health basic scientists) have been recruited. Female and minority investigators are also well-represented. In order to develop a comprehensive strategy to move the field of environmental hepatology forward, it is necessary to first assemble experts who would otherwise not interact with each other to discuss current mechanistic data and identify knowledge gaps. To this end, greater than 100 attendees from industry, academics (including students and early stage investigators), and government are expected. Conference proceedings will be published in a scientific journal. This symposium is relevant to all physicians or scientists who either care for patients with liver disease or perform research in liver disease or environmental health science.

描述（由申请人提供） 肝脏是最大的内脏器官，也是最复杂的，因为它调节异生物质和能量代谢。 然而，肝病越来越常见，目前基于人群的研究表明，超过1/3的成年人和超过10%的儿童患有慢性肝病。据推测，由于其在异生物质代谢中的作用，肝脏是目标 最常受环境化学物质影响的器官。 然而，环境暴露在当前肝病流行中的作用同时被临床医生和科学研究界认识不足。本次申请的主要目的是举办为期两天的“环境化学品与肝病”研讨会。在过去的五年里（如果有的话），没有关于环境肝病学新兴领域的全面会议。已招募了一个教员参与者专家小组，并计划举办26次讲座和一次海报会议。值得注意的是，已经招募了具有不同专业背景的教师参与者（从临床肝病学家到环境卫生基础科学家）。女性和少数民族调查员也有相当多的代表。为了制定一项全面的战略来推动环境肝病学领域的发展，有必要首先聚集否则不会相互交流的专家，以讨论当前的机制数据并确定知识差距。为此，预计将有100多名来自行业，学术界（包括学生和早期研究人员）和政府的与会者。会议记录将在一份科学杂志上发表。本次研讨会与所有关心肝病患者或从事肝病或环境健康科学研究的医生或科学家相关。