Gaze Stability in Children with Hearing and Vestibular Loss

听力和前庭丧失儿童的凝视稳定性

• 批准号: 8662906
• 负责人: Kristen L. Janky
• 金额: $ 20.36万
• 依托单位: FATHER FLANAGAN'S BOYS' HOME
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8662906
• 关键词: Activities of Daily Living; Address; Adult; Affect; Age; Attention; Bilateral; Child; Childhood; Cochlear Implants; Communication; Data; Development; Developmental Delay Disorders; Diagnosis; Early Intervention; Early identification; Effectiveness; Etiology; Financial compensation; Future; Goals; Habilitation; Head; Head Movements; Hearing; Impairment; Intervention; Investigation; Knowledge; Language; Lead; Low Prevalence; Measures; Motion; Motor; Organ; Perception; Performance; Population; Prevalence; Process; Quality of life; Reading; Reporting; Research; Risk; Role; Saccule and Utricle; Semicircular canal structure; Sensory; Severities; Social Development; Social Interaction; Speech; Speed; Sum; System; Testing; Vestibular loss; Visual Acuity; Walking; Work; base; experience; falls; gaze; hearing impairment; implantation; large print; novel strategies; otoconia; programs; response; success; vestibulo-ocular reflex

In children withi hiearing loss (CHL), the presence of vestibular loss may result in gross motor developmental delay and reduced visual acuity, requiring additional habilitation. However, vestibular testing is not routine in the pediatric population, and vestibular habilitation is seldom considered for CHL. The longterm goal of this research program is to diagnose and then minimize the impact of vestibular loss in CHL. As a first step, the objectives in the present proposal are to characterize vestibular function in CHL, and investigate the effect of vestibular loss on static (head stable) and dynamic (head in motion) visual acuity in these children. The central hypothesis is that both static visual acuity (SVA) and dynamic visual acuity (DVA) are degraded in CHL with vestibular loss. This hypothesis is based on research in adults with vestibular loss, who experience reduced visual acuity with standing, walking and head movement, which impairs activities of daily living. The rationale for the proposed research is that reduced visual acuity, especially in the classroom, may impair academic success in CHL. Preliminary data obtained in our lab suggests that visual acuity is reduced in CHL. Two specific aims will be addressed in this proposal: 1) we will characterize vestibular loss in CHL, and 2) we will evaluate the effect of vestibular loss on SVA and DVA in these children. We will focus on CHL who use a cochlear implant (CI), who have increased risk of vestibular loss due to implantation and etiology of hearing loss. This provides a population of CHL with vestibular loss where visual acuity can be better studied. In Aim 1, a new approach for assessing semicircular-canal function that has been developed for use in adults will be evaluated in children. Additionally, the relationship between severity of vestibular loss and gross motor performance will be investigated. In Aim 2, SVA and DVA will be assessed while sitting and under increasing demands of maintaining upright stance. This work will provide new knowledge regarding the prevalence of vestibular loss and the extent to which vestibular loss affects visual acuity in CHL. This will further advance our understanding of the natural compensation process of vestibular loss in CHL and lead to further investigations regarding the identification, implications, and habilitation of vestibular loss in CHL.

在听力损失(CHL)的儿童中，前庭损失的存在可能导致大运动 发育迟缓和视力下降，需要额外的康复。然而，前庭测试 这在儿科人群中并不是常规的，前庭康复很少被考虑用于CHL。从长远来看 这项研究的目标是诊断并尽量减少慢性淋巴细胞性白血病前庭缺失的影响。AS 第一步，本提案的目标是表征CHL的前庭功能，以及 前庭功能丧失对老年人静态(头部稳定)和动态(头部运动)视力的影响 这些孩子。中心假设是静态视力(SVA)和动态视力(DVA) 在伴有前庭缺失的CHL中降解。这一假设是基于对患有前庭功能丧失的成年人的研究， 他们因站立、行走和头部运动而视力下降，这会损害 日常生活。提出这项研究的理由是，视力下降，特别是在课堂上， 可能会损害CHL的学业成就。我们实验室获得的初步数据表明，视力是 降低了CHL。在这项提案中将涉及两个具体目标：1)我们将描述前庭损失的特征 2)我们将评估前庭缺失对这些儿童SVA和DVA的影响。我们将专注于 对于使用人工耳蜗(CI)的CHL患者，他们因植入和植入而增加前庭损失的风险 听力损失的病因学。这为CHL人群提供了前庭功能丧失，其中视力可能是 更好地学习。在目标1中，已经开发了一种评估半规管功能的新方法 用于成人的将在儿童中进行评估。此外，前庭丢失的严重程度与 并将对粗大运动性能进行调查。在目标2中，SVA和DVA将在坐和 在保持直立姿态的要求越来越高的情况下。这项工作将提供关于以下方面的新知识 CHL患者前庭功能丧失的发生率以及前庭功能丧失对视力的影响程度。这将是 进一步加深了我们对CHL前庭缺失的自然补偿过程的理解，并导致 关于CHL前庭缺失的识别、影响和康复的进一步研究。