Effects of Social Context, Culture and Minority Status on Depression and Anxiety

社会背景、文化和少数民族地位对抑郁和焦虑的影响

• 批准号: 8664936
• 负责人: MARGARITA ALEGRIA
• 金额: $ 61.08万
• 依托单位: CAMBRIDGE HEALTH ALLIANCE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-31 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8664936
• 关键词: Acculturation; Adolescence; Adult; Affect; Age; Anxiety; Anxiety Disorders; Asian Americans; Caring; Childhood; Communities; Community based prevention; Data; Data Collection; Databases; Depressive disorder; Discrimination; Disease; Encapsulated; Epidemiologic Studies; Ethnography; Experimental Designs; Exposure to; Family; Family history of; Goals; Healthcare; Individual; Intervention; Interview; Island; Knowledge; Latino; Life; Link; Long-Term Effects; Longitudinal Studies; Major Depressive Disorder; Measures; Mediating; Mental Depression; Mental Health; Mental disorders; Minority; Minority Groups; Modeling; NIH Program Announcements; Neighborhoods; Nomads; Onset of illness; Outcome; Parents; Participant; Play; Positioning Attribute; Prevalence; Process; Public Health; Puerto Rican; Puerto Rico; Research Design; Risk; Role; Site; Social Environment; Strategic Planning; Stratification; Stress; Symptoms; Techniques; Testing; Variant; Violence; Youth; aged; critical period; depressive symptoms; early adolescence; early experience; emerging adult; ethnic difference; experience; follow-up; functional disability; health disparity; member; mental development; physical conditioning; population health; prevent; racial/ethnic difference; response; social; young adult

DESCRIPTION (provided by applicant): The proposed project investigates the social mechanisms behind ethnic/racial differences in the prevalence of major depression disorder (MDD) and depressive and anxiety symptoms (DAS) in Latino young adults (ages 17-25). We propose to extend the path-breaking Boricua study to examine if experiences of minority status and acculturation are causally linked to differences in prevalence of MDD/DAS across Island versus mainland Puerto Ricans. Since Puerto Ricans are a minority in the South Bronx in NY but a majority on the Island of Puerto Rico, this migrant study design enables us to use variation across sites as a way to examine the causal mechanism of minority status and acculturation on mental health outcomes. Our planned study also includes a wide range of environmental, social, family, and individual level measures associated with MDD and DAS, and uses advanced statistical techniques to identify the risks and protective factors for these negative outcomes. We propose to conduct follow-up interviews with parents and with young adults now ages 17-25 who participated in the Boricua study. Using these data, we will conduct quantitative analysis to: 1) determine the causal impact of minority status as contrasted to majority status, 2) identify the mechanisms behind the effect of minority status on subsequent MDD and DAS, and 3) test conditions that moderate the causal link between minority status and environmental and social context. We will supplement the quantitative analysis with in- depth qualitative interviews and ethnographic neighborhood observation to deepen our understanding of the quantitative findings and identify minority status experiences and acculturation stresses potentially related to changes in MDD and DAS, as well as functional impairment. At the close of our study we intend to create a public-use database of the four waves of Boricua study. This would be the first longitudinal study to assess the causal effects of early experiences of minority status and acculturation on Latino young adult mental illness. Our ultimate goal is to generate information to reduce mental illness in minority communities.

描述（由申请人提供）：拟议的项目研究了拉丁裔年轻人（17-25岁）的大抑郁症患病率（MDD）（MDD）（MDD）（MDD）（MDD）和抑郁和焦虑症状（DAS）背后的社会机制。我们建议扩展破坏性的Boricua研究，以检查少数群体地位和适应的经历是否与岛上MDD/DAS在岛上与大陆波多黎各人的患病率差异有关。由于波多黎各人在纽约州南布朗克斯是少数群体，但在波多黎各岛上是大多数人，因此这项移民研究设计使我们能够利用跨站点的变异来研究少数群体地位的因果机制和对精神健康兴趣成果的因果机制。我们计划的研究还包括与MDD和DAS相关的各种环境，社会，家庭和个人水平措施，并使用先进的统计技术来确定这些负面结果的风险和保护因素。我们 建议对父母和现在参加Boricua研究的17-25岁的年轻人进行后续采访。使用这些数据，我们将进行定量分析至：1）确定少数族裔状况与多数状态形成对比的因果关系，2）确定 少数群体身份对随后的MDD和DA的影响背后的机制，以及3）测试条件，以减轻少数群体状况与环境和社会环境之间的因果关系。我们将通过深入的定性访谈和人种学邻里的观察来补充定量分析，以加深我们对定量发现的理解，并确定少数群体地位的经验和适应应力，这可能与 MDD和DAS的变化以及功能障碍。在研究结束时，我们打算为Boricua研究的四波研究创建一个公共用途数据库。这将是第一项评估少数群体状况和适应对拉丁裔年轻成人精神疾病的早期经历的因果影响的纵向研究。我们的最终目标是生成信息以减少少数民族社区的精神疾病。