Integrating Resistant Starch, Microbiome and Disease

项目摘要 “整合抗性淀粉、微生物组和疾病风险”国际研讨会 2014年5月14日至16日，在爱荷华州的艾姆斯提出了“减少”的建议，以探索关于发展和 膳食抗消化淀粉的化学，掺入人类食物，以及 抗性淀粉对慢性健康状况的风险，包括糖尿病，结肠癌和肥胖， 可能受胃肠影响的疾病，即，肠道微生物组抗性淀粉 研究整合了农业中关于植物遗传修饰以促进健康的推力， 人类健康对肠道微生物组的饮食调节。本次研讨会的计划领域是 与FDA食品安全和营养中心直接相关，因为它专注于科学 开发抗性淀粉（一种膳食纤维）以降低人类疾病风险的背后。这 研讨会将为工业界及学术界人士提供有关植物的宝贵资料 淀粉的健康、化学和生物学改性;富含抗性淀粉的安全食品的开发 淀粉;微生物学家，营养学家和食品科学家在饮食和健康领域的工作。的 研讨会包括21个口头报告在七个会议：植物育种和遗传学，化学， 食品开发，对微生物组的影响，以及降低结肠风险的抗性淀粉 癌症、糖尿病和肥胖。每场会议包括3名发言人，其中一名发表主题演讲。轮 第1天和第3天举行圆桌讨论，第2天举行海报讨论会。爱荷华州州立大学的赞助商将 包括生物技术办公室和植物科学研究所以及各个学术部门。 本地学生可获豁免学费，其他学生可获豁免学费及交通赠款， 强调代表性不足的少数群体成员。预期成果包括： 的最先进的知识抗性淀粉，出版专著作为国家的最先进的记录， 会议的时间和令人鼓舞的综合研究的发展，这将有助于快速 抗性淀粉的开发及其在改善人类健康方面的应用进展。

Project Summary An international symposium "Integrating Resistant Starch, Microbiome, and Disease Risk Reduction," is proposed in Ames, Iowa, May 14-16, 2014 to explore research on the development and chemistry of dietary digestion-resistant starches, incorporation into human foods, and the impacts of resistant starch on the risk for chronic health conditions, including diabetes, colon cancer and obesity, diseases that are potentially influenced by the gastrointestinal, i.e., gut, microbiome. Resistant starch research integrates thrusts in agriculture on plant genetic modifications for health promotion and in human health on the dietary modulation of the gut microbiome. The program area of this symposium is directly relevant to FDA's Center for Food Safety and Nutrition because of its focus on the science behind developing resistant starch, a form of dietary fiber, for reducing the risk of human disease. This symposium will provide valuable information to scientists in industry and academia targeting plant modifications for health, chemistry and biology of starch; development of safe foods enriched in resistant starch; and microbiologists, nutritionists, and food scientists working in areas of diet and health. The symposium includes 21 oral presentations in seven sessions: plant breeding and genetics, chemistry, food product development, impact on the microbiome, and resistant starch for reduction of risk for colon cancer, diabetes, and obesity. Each session includes 3 speakers, one giving a keynote address. Round table discussions are on days 1&3 and a poster session is on day 2. Iowa State University sponsors will include the Office of Biotechnology and the Plant Sciences Institute and individual academic departments. Fees will be waived for local students and fee waiver plus travel grants will be offered to other students, emphasizing members of under-represented minority groups. Expected outcomes include providing state- of-the-art knowledge about resistant starch, publishing a monograph as a record of the state-of-the-art at the time of the conference and encouraging development of integrative research that will facilitate rapid progress in resistant starch development and its application to improved human health.