IGF::OT::IGF SBIR Topic 58, Phase II - High-Voltage Li-ion Battery for Left Ventricular Assist Device Power

IGF::OT::IGF SBIR 主题 58，第二阶段 - 用于左心室辅助装置电源的高压锂离子电池

• 批准号: 8937268
• 负责人: CASTRO LAICER
• 金额: $ 99.6万
• 依托单位: GINER, INC.
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-14 至 2016-07-13
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8937268
• 关键词: Address; Cells; Charge; Devices; Frequencies; Heart; Heart Transplantation; Hybrid Cells; Implant; Ions; Left; Manufacturer Name; Patients; Performance; Phase; Pump; Quality of life; Small Business Innovation Research Grant; System; Time; operation; ventricular assist device; voltage

Left ventricular assist devices (LVADs), originally developed as a bridge to heart transplants, are gaining wider use in long-term therapy. A critical component is the external Li-ion battery pack that powers the implanted pump through a percutaneous cable. Major drawbacks of current LVAD batteries which this project addresses, include the need for patients to carry heavy and bulky batteries, the high frequency with which batteries need recharging, and slow recharging rates. Device manufacturers employ standard, off-the-shelf batter cells that are not tailored for optimal performance under specific LVAD operation conditions; thus there is significant room for improvement in these power systems to enhance heart patient mobility and quality of life.

左心室辅助装置（LVAD）最初是作为心脏移植的桥梁而开发的，目前正在长期治疗中得到更广泛的应用。一个关键组件是通过经皮电缆为植入泵供电的外部锂离子电池组。本项目解决的当前LVAD电池的主要缺点包括患者需要携带笨重的电池，电池需要充电的频率高，以及充电速率慢。设备制造商采用标准的现成电池，这些电池在特定LVAD操作条件下没有针对最佳性能进行定制;因此，这些电源系统在提高心脏病患者的移动性和生活质量方面有很大的改进空间。