SkyScan 1176 Micro CT System

SkyScan 1176 微型 CT 系统

• 批准号: 8639928
• 负责人: JAMES C WILLIAMS
• 金额: $ 38.29万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-15 至 2015-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8639928
• 关键词: Animals; Data; Equipment; Family suidae; Funding; Heart; Human; Image; Indiana; Institutes; Kidney; Laboratories; Monitor; Protocols documentation; Recording of previous events; Research Personnel; Scanning; Science; Specimen; System; Time; Tissues; United States National Institutes of Health; Work; X-Ray Computed Tomography; bioimaging; in vivo; pressure

DESCRIPTION (provided by applicant): This proposal is for the purchase of a SkyScan 1176 In-vivo Micro CT system, which will add new capabilities to our core of users. The seventeen laboratories collaborating in this venture are involved in a wide range of NIH-funded ventures, and we have a history of working together successfully in this shared facility. To facilitate administration of this shared equipment we have partnered with the Indiana Institute for Biomedical Imaging Sciences, who provide campus-wide assistance with biomedical imaging. The request for a Skyscan 1176 system has a three-fold rationale: adding in vivo scanning capability, allowing large specimen ex vivo scanning, and reducing capacity on the present CT system. The present micro CT system (a SkyScan 1172, obtained in 2007) provides excellent imaging of mineralized tissues, but can be used only for ex vivo specimens. The SkyScan 1176 will enable researchers to utilize experimental protocols that can monitor the changes in tissue over time in their experimental animals, thereby provided longitudinal data while simultaneously using fewer animals. The SkyScan 1176 will also allow the scanning of larger intact specimens (like pig hearts and human kidneys) which cannot be accommodated on the present system. With regard to capacity, the present system cannot handle the high volume of micro CT imaging demanded by NIH-funded projects on this campus. The SkyScan 1176 can be used to scan many of the specimens now being scanned on the old 1172 system, with identical parameters, and so relieve pressure on the present facility. The SkyScan 1176 system is complementary to the presently existing system. This means that minimal retraining will be required for present users. Moreover, for most users the two systems can be used interchangeably, so that the present full load on the existing system can be relieved, thus allowing every laboratory to obtain data on its specimens in a timely manner.

描述（由申请人提供）：该建议旨在购买Skyscan 1176 In-Vivo Micro CT系统，该系统将为我们的用户核心增加新功能。在这项合作中合作的17个实验室参与了广泛的NIH资助合资企业，我们有在这个共享设施中成功合作的历史。为了促进这种共享设备的管理，我们与印第安纳州生物医学成像科学研究所合作，后者在校园内为生物医学成像提供帮助。 Skyscan 1176系统的请求具有三倍的理由：添加体内扫描功能，允许大型样品实行体内扫描，并降低当前CT系统的容量。当前的微型CT系统（2007年获得的Skyscan 1172）提供了矿化组织的出色成像，但仅用于离体试样。 Skyscan 1176将使研究人员能够利用可以监测其实验动物组织随时间变化的实验方案，从而提供纵向数据，同时使用较少的动物。 Skyscan 1176还将允许扫描较大的完整标本（例如猪心和人肾脏），该标本无法容纳在当前系统上。关于容量，目前的系统无法处理该校园内NIH资助的项目所需的大量微型CT成像。 Skyscan 1176可用于扫描许多现在在旧1172系统上扫描的标本，具有相同的参数，因此可以减轻当前设施的压力。 Skyscan 1176系统与当前现有系统互补。这意味着目前的用户需要最少的再培训。此外，对于大多数用户而言，两个系统可以互换使用，以便可以放松现有系统上的当前负载，从而允许每个实验室及时获取标本的数据。