Histology Core

组织学核心

• 批准号: 8667809
• 负责人: BRUCE Thomas VOLPE
• 金额: $ 21.72万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8667809
• 关键词: Animals; Apical; Apoptosis; Brain; Cells; Cerebrum; Cognitive; Cytokine Receptors; Dendrites; Dendritic Spines; Encephalitis; Ensure; Goals; Histologic; Histology; Image; Immune; Immunohistochemistry; Impaired cognition; Impairment; In Situ Hybridization; Inflammation; Instruction; Measures; Methods; Mus; Nerve Degeneration; Neurons; Neurotransmitter Receptor; Oils; Procedures; Research Personnel; Sepsis; Stress; Structure; Survivors; Synapses; Techniques; Tissues; Transcript; base; behavioral impairment; brain tissue; cost; cytokine; investigator training; multi-photon; receptor

Histology - Core D Mice surviving sepsis display prolonged inflammation in the brain. The Histology Core will provide high quality immunohistochemistry and in situ hybridization of brain tissue to assess brain inflammation and histologic correlates of impaired behavior or cognition. The availability of a Core for these procedures will ensure comparability across all projects and will be cost saving.

组织学- Core D败血症存活的小鼠在大脑中表现出长期的炎症。组织学核心将提供高质量的免疫组织化学和脑组织原位杂交，以评估脑炎症和受损行为或认知的组织学相关性。这些程序的核心可用性将确保所有项目之间的可比性，并将节省成本。