Gulf South Minority-based NCI Community Oncology Research Program

描述 3 总体审查标准和影响 3 融资机会公告（FOA）特定标准 10 组织和结构 10 临床试验研究 12 癌症护理交付研究 13 运营/数据管理 15 人类受试者注意事项 17 妇女、少数民族和儿童的融入 17 资源共享 17 预算和支助期 17 特别强调小组名册 描述（由申请人提供）：海湾南部少数民族为基础的NCI社区肿瘤学研究计划（GS-MB-NCORP）汇集了来自路易斯安那州两个少数民族为基础的CCOP（MBCCOP）和一个NCCCP站点的综合临床试验计划，得到了完善和资助的癌症护理提供研究以及健康差异和基于社区的预防性研究计划的支持。由路易斯安那州立大学新奥尔良医学院（LSUHSC-NO-MBCCOP）及其NCCCP合作伙伴玛丽伯德帕金斯癌症中心-巴吞鲁日的湖医院圣母院（MBP-OLOL）建立的MBCCOP与路易斯安那州西北部什里夫波特路易斯安那州立大学医学院（LSUHSC-SH-MBCCOP）的MBCCOP一起创建了GS-MB-NCORP。该联盟整合了成熟且经验丰富的临床医生和研究人员团队，旨在通过领先的学术和社区医院网络，为我们所服务的患者提供最先进的癌症临床试验。路易斯安那州是美国癌症患者生存率最低的地区之一，尽管并非所有类型的癌症发病率最高。这对于服务不足和少数民族患者尤其如此，明显反映了重大的健康差距。对这种差异的可能解释包括社会经济和获得保健的机会，以及对遗传和生物差异知之甚少。LSU MBCCOPs和MBP-OLOL的NCCCP独立工作，以增加少数民族和服务不足社区的临床试验，建立外展和教育计划，并扩大癌症护理交付研究和健康差异研究。2012年秋季，我们同意将我们的优势和经验联合收割机整合到GS-MB-NCORP中，目标是通过整合我们的临床试验计划并将癌症护理交付和健康差异研究人员纳入临床试验过程，对癌症相关的健康差异产生更显著的影响。GS-MB-NCORP的目标是增加少数民族和服务不足人群在临床试验中的参与，确定参与的障碍，并将社区纳入研究。为此，我们提出以下具体目标。1)推进癌症临床试验准入的综合系统，促进和便利患者的参与和登记，特别是路易斯安那州服务不足和少数族裔人群。2)促进癌症护理提供研究计划，以确保我们有能力参与研究基地提出的研究计划，并最终设计出改善患者护理的方案。3)通过社区参与扩大健康差异研究计划，以增加少数民族和服务不足人群在临床试验中的参与

DESCRIPTION 3 OVERALL REVIEW CRITERIA AND IMPACT 3 FUNDING OPPORTUNITY ANNOUNCEMENT (FOA) SPECIFIC CRITERIA 10 ORGANIZATION AND STRUCTURE 10 CLINICAL TRIALS RESEARCH PROGRAM 12 CANCER CARE DELIVERY RESEARCH PROGRAM 13 OPERATIONS/DATA MANAGEMENT 15 PROTECTIONS FOR HUMAN SUBJECTS 17 INCLUSION OF WOMEN, MINORITIES, AND CHILDREN 17 RESOURCE SHARING PLAN 17 BUDGET AND PERIOD OF SUPPORT 17 SPECIAL EMPHASIS PANEL ROSTER DESCRIPTION (provided by applicant): The Gulf South-Minority Based-NCI Community Oncology Research Program (GS-MB-NCORP) brings together an integrated clinical trials program from two Minority Based CCOPs (MBCCOP) and an NCCCP site in the state of Louisiana, supported by well-established and funded Cancer Care Delivery Research and programs in Health Disparities and Community-Based Participatory Research. The MBCCOP established by the LSU School of Medicine in New Orleans (LSUHSC-NO-MBCCOP) and its NCCCP partner, the Mary Bird Perkins Cancer Center - Our Lady of the Lake Hospital (MBP-OLOL) in Baton Rouge, have joined the MBCCOP at the LSU School of Medicine in Shreveport (LSUHSC-SH-MBCCOP) in northwest Louisiana to create the GS-MB-NCORP. This consortium integrates well-established and experienced teams of clinicians and researchers with the aim of expanding access to state-of-the-art cancer clinical trials to the patients we serve, through a network of leading academic and community hospitals. Louisiana has one of the poorest survival rates for cancer patients in the United States, despite not having the highest incidence for all types of the disease. This is particularly true for underserved and minority patients, clealy reflecting a major health disparity. Possible explanations for this disparity range from socio-economic and access to health care, to poorly understood genetic and biological differences. The LSU MBCCOPs and the NCCCP at MBP-OLOL have independently worked to increase access to clinical trials for minority and underserved communities, establish outreach and education programs, and expand Cancer Care Delivery Research and Health Disparity studies. In the fall of 2012, we agreed to combine our strengths and experience into the GS-MB-NCORP with the goal of having a more significant impact on cancer associated health disparities by integrating our clinical trials programs and incorporating Cancer Care Delivery and Health Disparity researchers into the clinical trials process. The GS-MB-NCORP's goals are to increase the participation of minorities and underserved populations in clinical trials, identify barriers t participation, and incorporate the community in the research studies. To achieve this, we propose the following Specific Aims. 1) Advance an integrated system of access to cancer clinical trials that promote and facilitate the participation and enrollment of patients, in particlar underserved and minority populations in Louisiana. 2) Promote Cancer Care Delivery Research Programs to ensure our ability to participate in research initiatives proposed by the Research Bases, and eventually design protocols that improve the care of our patients. 3) Expand Health Disparities Research programs through community engagement to increase the participation of minority and underserved populations in clinical trials