Gulf South Minority/Underserved Clinical Trials Network (Gulf South M/U CTN)

总体而言，癌症患者患COVID-19的风险增加。癌症和COVID-19都不成比例地影响着全国各地的少数民族和服务不足的人群，特别是在路易斯安那州和密西西比的海湾南部地区。这些重大的健康差距在生活在农村地区和集中的弱势（高度贫困）地区的癌症患者中进一步扩大。因此，迫切需要建立一个新的路易斯安那州癌症-COVID-19（LA-Cancer-COVID-19 Registry）登记系统，以更好地了解当前大流行对海湾南部地区癌症患者的影响。获得的数据将用于了解COVID-19如何影响现有的癌症健康差异，并将为我们制定新的国家诊断和治疗计划做好准备。该补充的母公司补助金是海湾南部少数民族/服务不足的临床试验网络（海湾南部CTN）NCORP。Gulf South CTN是路易斯安那州立大学新奥尔良癌症中心、Ochsner诊所基金会、玛丽·伯德·帕金斯癌症中心和路易斯安那州立大学位于什里夫波特的费斯特·韦勒癌症中心的合作伙伴。他们共同监督一个由44个临床站点组成的网络，这些站点显著增加了整个地区癌症患者的临床试验注册人数。大约50%的患者是非洲裔美国人。路易斯安那州肿瘤登记处（LTR），SEER登记处，也是海湾南部CTN的合作伙伴。LTR收集该州癌症患者的所有信息，并有法律授权访问他们的所有生物样本和临床信息。出于本补充文件的目的，LTR和负责监督COVID-19应对工作的路易斯安那州卫生部公共卫生办公室已同意建立这一新的登记处。因此，具体目标是：1）通过将LTR癌症登记与路易斯安那州卫生部（LDH）COVID-19登记联系起来，开发路易斯安那州癌症- COVID-19登记。2)使用新登记处的数据研究COVID-19对路易斯安那州癌症健康差异的影响，以及3）通过路易斯安那州癌症COVID-19登记处的协调数据收集工作，更有效地参与国家临床和流行病学研究。洛杉矶癌症-COVID-19登记系统将使我们能够识别患有COVID-19的癌症患者，并识别感染的高风险人群，以及确定冠状病毒“热点”的位置。我们将能够确定COVID-19如何影响不同人群以及农村与城市地区的癌症健康差异。更重要的是，癌症-COVID-19登记中心将通过快速部署诊断、治疗或流行病学试验，为我们更好地应对COVID-19或其他未来大流行病的卷土重来做好准备。

Cancer patients overall are at increased risk for developing COVID-19. Both cancer and COVID-19 disproportionately affect minority and underserved populations throughout the country and especially in the Gulf South region of Louisiana and Mississippi. These major health disparities are further magnified in cancer patients living in rural areas and regions of concentrated disadvantage (high poverty). Therefore, there is an urgent need to develop a new Louisiana Cancer-COVID-19 (LA-Cancer-COVID-19 Registry) registry to better understand the impact of the current pandemic on cancer patients in the Gulf South Region. The data obtained will be used to understand how COVID-19 has affected existing cancer health disparities and will prepare us for new national diagnostic and treatment initiatives. The parent grant to this supplement is the Gulf South Minority/Underserved Clinical Trials Network (Gulf South CTN) NCORP. The Gulf South CTN is a partnership between LSU Cancer Center – New Orleans, Ochsner Clinic Foundation, Mary Bird Perkins Cancer Center and LSU- Feist Weiller Cancer Center in Shreveport. Together they oversee a network of 44 clinical sites that have significantly increased enrollments of cancer patients into clinical trials throughout the region. Approximately 50% of patients enrolled are African American. The Louisiana Tumor Registry (LTR), a SEER registry, is also a partner in the Gulf South CTN. The LTR collects all information on cancer patients in the state and has legislative mandate to access all their biological samples and clinical information. For the purpose of this Supplement, the LTR and the Office of Public Health at the Louisiana Department of Health, that oversees the response to COVID-19, have agreed to build this new registry. Therefore the Specific Aims are: 1) Develop the Louisiana Cancer – COVID-19 Registry by linking the LTR cancer registry with the Louisiana Department of Health (LDH) COVID-19 registry. 2) Use the data from the new registry to study the effect of COVID-19 on cancer health disparities in Louisiana, and 3) More effectively participate in national clinical and epidemiological studies through the coordinated data collection efforts of the Louisiana CancerCOVID-19 Registry. The LA-Cancer-COVID-19 Registry will allow us to identify cancer patients who have developed COVID-19 and identify those at high risk for developing the infection and to determine the location of coronavirus “hot spots”. We will be able to determine how COVID-19 impacts cancer health disparities in different populations and in rural vs urban locations. More importantly the Cancer-COVID19 Registry will better prepare us for a resurgence of COVID-19 or other future pandemics by rapidly deploy being able to deploy diagnostic, treatment or epidemiological trials.