Administrative Core

行政核心

• 批准号: 10005249
• 负责人: AUGUSTO C. OCHOA
• 金额: $ 20.78万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-19 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10005249
• 关键词: Achievement; Address; Advisory Committees; Advocacy; Affect; Applications Grants; Basic Science; Biological; Biomedical Research; Birds; Cancer Center; Cancer Center Planning Grant; Cancer Etiology; Charge; Clinic; Clinical; Clinical Research; Clinical Trials; Collaborations; Committee Members; Communication; Data; Development; Ensure; Evaluation; Fostering; Funding; Future; Genetic; Goals; Grant; Institution; Institutional Review Boards; Intellectual Property; Lead; Leadership; Logistics; Louisiana; Malignant Neoplasms; Minority; Monitor; NCI Center for Cancer Research; Patients; Personnel Management; Persons; Population Sciences; Preparation; Principal Investigator; Protocols documentation; Research; Research Activity; Research Personnel; Research Project Grants; Research Support; Resource Sharing; Schedule; Series; Translational Research; Universities; Update; Visit; biobank; cancer clinical trial; cancer health disparity; cancer therapy; experience; health disparity; high standard; implementation research; improved; improved outcome; meetings; member; multidisciplinary; novel strategies; programs; research and development; response; social; social determinants; tumor; tumor registry

ABSTRACT – Administrative Core The Gulf South Center for Research and Solutions in Cancer Health Disparities (Gulf South-CARES-CHD) brings together investigators from academic and clinical research institutions in Louisiana, led by the Louisiana State University Cancer Center – New Orleans (LSU CC-NO), to advance translational research on the genetic, biological and social mechanisms that promote and sustain cancer health disparities. The Administrative Core (AC) will facilitate the organization and implementation of the goals set by the leadership team. It will facilitate the contributions of investigators of the Louisiana Cancer Research Center (LCRC), the member institutions of the Gulf South – NCORP, and the Pennington Biomedical Research Center – all of which conduct research in cancer health disparities. Through the use of biospecimens provided mainly by the LCRC Tumor Biorepository, and patient information provided by the Louisiana Tumor Registry (LTR), investigators have been conducting research to understand the genetic, biological and social determinants that promote cancer health disparities in our region. With the leadership of the Co-PI/PD's and the Executive Committee, the AC will provide central oversight, coordination, support and logistics to investigators participating in the Gulf South- CARES-CHD research program. To achieve this, the AC has the following objectives: a) oversee research planning and implementation through regular meetings; b) coordinate and monitor pilot research projects; c) foster productive interactions among collaborators; d) ensure the highest standards of scientific integrity for all projects and program components and activities; e) stimulate new translational research collaborations related to health disparities; f) ensure horizontal and vertical integration among the programs and cores; and g) support the preparation of research projects and the submission of a future SPORE application. The AC is led by the contact PI and supported by a multidisciplinary team of established investigators that form the Executive Committee (EC). This leadership team is guided by an Internal Advisory Committee (IAB) comprised of academic researchers in various aspects of cancer and health disparities, as well as an External Advisory Committee (EAB) of SPORE investigators and leaders with expertise in the inclusion of minorities in cancer clinical trials. A series of planning and priority-setting steps have begun, with regular and ongoing in-person scientific meetings, to facilitate: 1) presentation and review of ongoing research in cancer health disparities, 2) planning of new RFAs for the submission and selection of Pilot Research Projects (PRP), 3) discussion of collaborations with existing P20's or SPOREs; and 4) planning future visits and reviews by Internal and External Advisory Board members. In summary, the AC facilitates the coordination and communication necessary for a seamless and mutually beneficial partnership among the participating members to advance the feasibility, planning and implementation of focused collaborations through the Gulf South CARES-CHD.

摘要-行政核心 墨西哥湾南部癌症健康差异研究和解决方案中心（Gulf South-CARES-CHD） 汇集了来自路易斯安那州学术和临床研究机构的研究人员，由路易斯安那州 州立大学癌症中心-新奥尔良（LSU CC-NO），以推进 遗传、生物和社会机制促进和维持癌症健康差异。的 行政核心（AC）将促进组织和实施领导层设定的目标 团队它将促进路易斯安那州癌症研究中心（LCRC）研究人员的贡献， 南海湾成员机构- NCORP和彭宁顿生物医学研究中心-所有这些 对癌症健康差异进行研究。通过使用主要由LCRC提供的生物样本 肿瘤生物储存库和路易斯安那州肿瘤登记处（LTR）提供的患者信息，研究者 一直在进行研究，以了解促进癌症的遗传，生物和社会决定因素 我们地区的健康差距。在Co-PI/PD和执行委员会的领导下，AC将 为参与海湾南部地区的调查人员提供中央监督、协调、支持和后勤保障， CARES-CHD研究计划。为此，咨询委员会有以下目标：a）监督研究 通过定期会议规划和执行; B）协调和监测试点研究项目; c） 促进合作者之间富有成效的互动; d）确保所有人的科学诚信的最高标准 项目和计划的组成部分和活动; e）刺激新的翻译研究合作， （f）确保各方案和核心方案之间的横向和纵向一体化;以及（g） 支持研究项目的准备和未来SPORE申请的提交。AC是LED 由联系PI执行，并由组成执行人员的多学科研究者团队提供支持 委员会（EC）。该领导团队由内部咨询委员会（IAB）指导， 学术研究人员在癌症和健康差距的各个方面，以及外部咨询 委员会（EAB）的SPORE研究人员和领导人的专业知识，在纳入少数民族癌症 临床试验一系列规划和确定优先事项的步骤已经开始，并定期和持续地与 科学会议，以促进：1）介绍和审查正在进行的癌症健康差异研究，2） 为提交和选择试点研究项目（PRP）规划新的RFA，3）讨论 与现有的P20或SPORE合作;以及4）计划内部和外部的未来访问和审查 咨询委员会成员。总而言之，咨询委员会促进以下方面所需的协调和沟通： 在参与成员之间建立无缝和互利的伙伴关系，以推进可行性， 通过海湾南部CARES-CHD规划和实施重点协作。