Investigating the potential of human stem cells to repair the degenerating auditory nerve after deafness

研究人类干细胞修复耳聋后退化听觉神经的潜力

• 批准号: nhmrc : 567117
• 负责人: Dr Bryony Nayagam
• 金额: $ 20.72万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-potential-human-nerve-deafness/116052
• 关键词: Investigating; potential; human; stem; cells

One in four Australians is predicted to experience some form of hearing loss by 2050. Hearing loss is irreversible and the chief clinical treatment available for severe to profound hearing loss is a cochlear implant. However, cochlear implant efficacy is limited by the degeneration of the auditory nerve following hearing loss. Using stem cells, this project will develop techniques to restore function to the auditory nerve through replacement of the specialised cells that comprise it.

据预测，到2050年，四分之一的澳大利亚人将经历某种形式的听力损失。听力损失是不可逆的，严重至极重度听力损失的主要临床治疗方法是人工耳蜗植入。然而，人工耳蜗植入的效果受到听力损失后听神经退化的限制。该项目将利用干细胞开发技术，通过替换组成听神经的专门细胞来恢复听神经的功能。