Investigating the relationship between Depression, Anxiety and Nausea and Vomiting during Pregnancy: Causation or shared liability?

调查怀孕期间抑郁、焦虑、恶心和呕吐之间的关系：因果关系还是共同责任？

• 批准号: nhmrc : GNT1084325
• 负责人: Dr Jodie Painter
• 金额: $ 58.35万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-relationship-depression-shared-liability/1345554
• 关键词: Investigating; relationship; between; Depression; Anxiety

Recent studies showing women who experience severe Nausea and vomiting during pregnancy (NVP) have higher rates of Anxiety and Depression prior to pregnancy have revived earlier hypotheses that NVP may have a psychogenic component. We hypothesize that Anxiety and Depression do not play a causal role in NVP but rather, the relationship is due to shared risk from genetic effects that influence both traits. We will test this hypothesis using genetic and epidemiological approaches.

最近的研究表明，怀孕期间经历严重恶心和呕吐(NVP)的女性在怀孕前焦虑和抑郁的几率更高，这再次提出了早期的假设，即NVP可能有心理原因。我们假设焦虑和抑郁在NVP中不起因果作用，相反，这种关系是由于影响这两个特征的遗传效应的共同风险所致。我们将使用遗传学和流行病学方法来检验这一假说。