A Health IT based Psychoeducational Intervention for African American Prostate Ca

基于健康信息技术的非裔美国人前列腺癌心理教育干预

• 批准号: 8774024
• 负责人: Brian M. Rivers
• 金额: $ 42.13万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-19 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8774024
• 关键词: African American; Aftercare; Anxiety; Apple; Area; Behavior Therapy; Biological Markers; Biopsy; Cancer Center; Cancer Patient; Clinical; Communication; Communities; Data; Diagnosis; Disease; Education; Family member; Goals; Health; Hydrocortisone; Individual; Information Services; Information Technology; Informed Consent; Intervention; Knowledge; Length; Malignant neoplasm of prostate; Maps; Measures; Mediating; Medical; Newly Diagnosed; Outcome; Outcome Study; Participant; Patient Self-Report; Patients; Personal Satisfaction; Play; Printing; Prostate; Prostatic Diseases; Psyche structure; Quality of life; Randomized Controlled Trials; Recruitment Activity; Reporting; Research; Risk; Role; SF-36; Sampling; Self Efficacy; Stress; Telephone Interviews; Telomerase; Therapy Evaluation; Time; Treatment Efficacy; Trust; Writing; base; cancer diagnosis; cancer education; cancer therapy; clinical practice; coping; disturbance in affect; experience; follow-up; health information technology; health related quality of life; improved; men; prognostic; psychoeducational intervention; psychologic; psychosocial; public health relevance; response; stressor; symptom management; telomere; theories; tool; treatment as usual

DESCRIPTION (provided by applicant): For African American (AA) men, in addition to being at increased risk for developing prostate cancer and dying from this disease, they also have an increased risk of experiencing poorer quality of life (QOL) after diagnosis in comparison to white men. Previous studies have demonstrated that men with newly diagnosed prostate cancer do want to be informed, yet patients continue to have unmet information needs. Information seeking has been demonstrated to play a critical role in individuals' efforts to cope with the disruption of QOL associated with cancer diagnosis and treatment. It has been well documented that AAs have limited access to recommended prostate cancer education and experience multiple barriers to receiving psychosocial information and services. Although a growing body of evidence suggests that psychoeducational interventions improve QOL among newly diagnosed prostate cancer patients, there remains a lack of research examining the efficacy of these interventions among AAs. More so, associations between prostate cancer anxiety and prognostic features for prostate cancer among AA have not been well investigated. As a result, the relationship of prostate cancer anxiety to the common determinants of QOL remains poorly understood. In response, we developed an Information Technology (IT) based Psychoeducational intervention, Personalized Health Information Navigator (PHIN), to enhance QOL of newly diagnosed prostate cancer patients. The objectives of this community-based randomized control trial are to examine the impact on QOL outcomes of a six-week community navigator (CN) guided health IT psychoeducational intervention (PHIN) versus print education (PE) among AA men who are newly diagnosed with prostate cancer. Men eligible to participate in the study are AA men ages18 to 75 who have a biopsy-confirmed diagnosis of prostate cancer. Eligible subjects will be identified within 2-months of their initial diagnosis from the Moffitt Cancer Center (MCC) and select community-based clinical practices located in the Tampa Bay area. Following provision of written informed consent, eligible subjects will be asked to complete a baseline telephone interview and will be contacted for follow-up telephone interviews at 6-weeks, 3-, 6- and 12-months following the baseline assessment. The improved QOL will be confirmed by self-reported data and measuring anxiety/stress related biomarkers, cortisol and telomeres. Previous studies reported that improved QOL by behavioral interventions was associated with changes in telomere length and cortisol.

描述(申请人提供)：对于非裔美国人(AA)男性，除了罹患前列腺癌和死于这种疾病的风险增加外，他们在确诊后经历较差生活质量(QOL)的风险也比白人男性更高。以前的研究表明，新诊断为前列腺癌的男性确实希望得到信息，但患者仍然有未得到满足的信息需求。事实证明，寻求信息在个人应对与癌症诊断和治疗相关的生活质量中断的努力中发挥着关键作用。已经有很好的记录表明，美国癌症协会接受推荐的前列腺癌教育的机会有限，在接受心理社会信息和服务方面遇到了多重障碍。尽管越来越多的证据表明心理教育干预改善了新诊断前列腺癌患者的生活质量，但仍缺乏研究检验这些干预措施在AA中的有效性。更重要的是，在再生障碍性贫血患者中，前列腺癌焦虑与前列腺癌预后特征之间的关系还没有得到很好的研究。因此，前列腺癌焦虑与生活质量的共同决定因素之间的关系仍然知之甚少。作为回应，我们开发了一种基于信息技术(IT)的心理教育干预，个性化健康信息导航器(Phin)，以提高新诊断的前列腺癌患者的生活质量。这项以社区为基础的随机对照试验的目的是检验社区导航员(CN)引导的健康IT心理教育干预(Phin)与印刷教育(PE)对新诊断为前列腺癌的AA男性患者生活质量结果的影响。有资格参加这项研究的男性是年龄在18岁到75岁之间、经活检确诊为前列腺癌的AA男性。符合条件的受试者将在首次诊断后2个月内从莫菲特癌症中心(MCC)确定，并选择坦帕湾地区的社区临床诊所。在提供书面知情同意后，将要求符合条件的受试者完成基线电话面试，并在基线评估后6周、3个月、6个月和12个月联系他们进行后续电话面试。改善的生活质量将通过自我报告的数据和测量与焦虑/压力相关的生物标记物、皮质醇和端粒来证实。以前的研究报道，通过行为干预改善生活质量与端粒长度和皮质醇的变化有关。