Motor Learning in a Customized Body-Machine Interface for Persons with Paralysis

为瘫痪者定制的身体-机器界面中的运动学习

• 批准号: 8638983
• 负责人: FERDINANDO Alessandro MUSSA-IVALDI
• 金额: $ 27.87万
• 依托单位: REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-10 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8638983
• 关键词: Algorithms; Attenuated; Cervical spinal cord injury; Cervical spinal cord structure; Characteristics; Clinical; Computers; Data; Development; Devices; Disabled Persons; Distal; Environment; Family; Goals; Hand; Individual; Injury; Interruption; Isometric Exercise; Joystick; Lead; Learning; Limb structure; Manuals; Maps; Measures; Methods; Metric; Moods; Motion; Motor; Motor Skills; Movement; Muscular Atrophy; Musculoskeletal Pain; Pain; Paralysed; Participant; Patients; Performance; Persons; Physical activity; Posture; Powered wheelchair; Process; Protocols documentation; Quadriplegia; Reflex action; Rehabilitation therapy; Research; Residual state; Self-Help Devices; Sensory; Shoulder; Signal Transduction; Simulate; Spinal cord injured survivor; Spinal cord injury; System; Testing; Time; Training; User-Computer Interface; Visceral; Vocabulary; Wheelchairs; arm; base; design; empowered; expectation; improved; mental state; motor learning; novel; novel strategies; operation; prevent; psychologic; sensor; skills; virtual

DESCRIPTION (provided by applicant): The goal of these studies is to enable persons paralyzed by spinal cord injury (SCI) to drive powered wheelchairs and interact with computers by acting through an interface that utilizes and adapts to their residual upper-body motor capabilities. This is called a "body-machine interface" because it maps the motions of the upper body -detected by wearable sensors- (arms and shoulders) to the space of device control signals in an optimal way. In this way, paralyzed persons who cannot operate a joystick controller because of lack of hand mobility can effectively use their whole upper body as virtual joystick device. An important characteristic of the proposed approach is that it incorporates an interactive learning process, in which the interface adapts to the subject's mobility and the subject learns to act through the interface. This study aims at developing and testing the customization of this interface to a group of SCI participants with tetraplegia, resulting from hig-level cervical injury. The proposed research is organized in three specific aims: (Aim 1) To develop new functional capabilities in persons with spinal cord injury by customizing a body- machine interface to their individual upper body mobility. After fitting the interface to the residal movements of each subject, participants will practice computer games aimed at training two classes of control actions: operating a virtual joystick and operating a virtual keyboard. This study will test the ability of the subjects to perform skilled maneuvers with a simulated wheelchair. (Aim 2.) To test the hypothesis that practicing the upper-body control of personalized interfaces results in significant physical and psychological benefits after spinal-cord injury. Rehabilitation of secondary complications is important in SCI. A study will evaluate and quantify the impact of the practicing functional upper-body motions on the mobility of the shoulder and arms by conventional clinical methods and by measuring the subjects' ability to generate coordinated upper body movements and to apply isometric forces. Other studies under this aim will evaluate the effects of operating the body-machine interface on musculoskeletal pain and on the mood and mental state of the participants. (Aim 3) To train spinal-cord injury survivors to skillfully operate a powered wheelchair using their enhanced upper body motor skills and customized interface parameters. The goal of this study is to transfer the skills learne in the virtual environment to the control of an actual powered wheelchair. After reaching stable performance in the simulated wheelchair, subjects will practice the control of the physical wheelchair via the same body-machine interface within safe a testing environment. If successful, this study will lead to effective operation of powered wheelchairs using a customized interface that adapts to the residual motor capability of its users. Physical and psychological benefits are expected to derive from the sustained and coordinated activity associated with the use of this body-machine interface

描述（由申请人提供）：这些研究的目标是使因脊髓损伤（SCI）而瘫痪的人能够驱动电动轮椅，并通过利用和适应其残余上身运动能力的界面与计算机进行交互。这被称为“身体-机器接口”，因为它将可穿戴传感器检测到的上半身（手臂和肩膀）的运动以最佳方式映射到设备控制信号的空间。这样，由于缺乏手部活动能力而无法操作操纵杆控制器的瘫痪者可以有效地将他们的整个上半身用作虚拟操纵杆装置。所提出的方法的一个重要特征是它结合了交互式学习过程，其中界面适应主体的移动性并且主体学习通过界面来行动。本研究旨在为一组因高位颈椎损伤而导致四肢瘫痪的 SCI 参与者开发和测试该界面的定制。拟议的研究分为三个具体目标：（目标 1）通过定制适合个人上半身活动能力的身体-机器接口，为脊髓损伤患者开发新的功能能力。在将界面与每个受试者的剩余动作相匹配后，参与者将练习旨在训练两类控制动作的计算机游戏：操作虚拟操纵杆和操作虚拟键盘。这项研究将测试受试者使用模拟轮椅进行熟练操作的能力。 （目标 2.）检验以下假设：练习个性化界面的上半身控制会在脊髓损伤后带来显着的身体和心理益处。继发并发症的康复对于 SCI 很重要。一项研究将通过传统的临床方法并通过测量受试者产生协调的上身运动和施加等长力的能力来评估和量化练习功能性上身运动对肩部和手臂活动性的影响。该目标下的其他研究将评估操作身体-机器界面对肌肉骨骼疼痛以及参与者情绪和精神状态的影响。 （目标 3）训练脊髓损伤幸存者利用增强的上半身运动技能和定制的界面参数熟练地操作电动轮椅。这项研究的目标是将在虚拟环境中学到的技能转移到实际电动轮椅的控制上。在模拟轮椅上达到稳定的性能后，受试者将在安全的测试环境中通过相同的身体-机器界面练习对物理轮椅的控制。如果成功，这项研究将使用适应用户剩余运动能力的定制界面来有效操作电动轮椅。与使用这种身体-机器界面相关的持续和协调的活动预计会带来身体和心理上的好处