Animal and Animal Food Diagnostic Sample Analysis in Support of FDA Vet-LRN Activ

机会#宾夕法尼亚大学PA-12-194-动物和动物食品诊断样本 支持FDA Vet-LRN活动和调查的分析 项目摘要/摘要 宾夕法尼亚大学动物诊断实验室系统(PADLS) 宾夕法尼亚州新博尔顿中心园区目前提供全面的兽医诊断服务 在鸟类和哺乳动物病理学、微生物学和毒理学领域。PADLS是完全认可的 由美国兽医实验室诊断师协会(AAVLD)和新博尔顿 中心设施是兽医实验室反应网络(VET-VET)的一级实验室成员 LRN)。除了保护宾夕法尼亚州联邦的动物和公民免受 除了对动物健康和食品安全的威胁外，该实验室还是一个关键的区域资源。 使其非常适合当前的VET-LRN项目提案。 我们的实验室在各种样品和基质类型的分析方面经验丰富，包括但不是 仅限于动物样本、环境样本、害虫、水以及动物和人类食品 以及谷物、肉类、鱼和牛奶等配料。当前的计划将受益于我们的 实验室的兽医诊断经验、专业知识和基础设施，我们将利用它们来 完成为该项目描述的工作。除了满足当前对增加的需求之外 发生涉及动物性食品的大规模疫情或威胁事件时的实验室能力 与药物有关的疾病或其他需要浪涌能力测试的大型紧急事件，PADLS 新的博尔顿中心实验室可以通过以下诊断活动进一步加强VET-LRN 更好地及早发现涉及国家食品安全和保障的新事件，并 促进快速反应，最大限度地减少伤害，最大限度地保护人类和动物健康。 我们的实验室为英联邦提供全面的兽医诊断服务 宾夕法尼亚州及周边地区。作为正常监测的一部分，要求进行一些分析 活动或常规尸检，而其他与过度、意外或 其他无法解释的动物损失或疾病。该实验室获得了AAVLD的完全认可，并 遵守他们对经认可的兽医诊断实验室的要求，会议 与实验室及其活动的所有方面有关的具体要求。AAVLD还要求 我们的实验室已经建立了质量体系，以记录政策、体系、计划和 程序。由于我们收到的样本矩阵的性质各不相同，我们正在不断改进 并改进我们的分析方法，以确保其敏感性和特异性。我们有信心 由于我们目前的资格和经验，我们有能力在这个项目中支持VET-LRN。 1

Opportunity #PA-12-194 University of Pennsylvania - Animal and Animal Food Diagnostic Sample Analysis in Support of FDA Vet-LRN Activities and Investigations PROJECT SUMMARY/ABSTRACT The Pennsylvania Animal Diagnostic Laboratory System (PADLS) located at the University of Pennsylvania's New Bolton Center campus currently offers comprehensive veterinary diagnostic services in the areas of avian and mammalian pathology, microbiology, and toxicology. PADLS is fully accredited by the American Association of Veterinary Laboratory Diagnosticians (AAVLD) and the New Bolton Center facility is a first-tier laboratory member of the Veterinary Laboratory Response Network (Vet- LRN). In addition to safeguarding the animals and citizens of the Commonwealth of Pennsylvania against threats to animal health and food safety, the laboratory also serves as a critical regional resource throughout the Eastern United States making it an excellent fit for the current Vet-LRN project proposal. Our laboratory is experienced in the analysis of a variety of sample and matrix types, including but not limited to animal samples, environmental samples, vermin, water, and animal and human food products and ingredients such as grain, meat, fish, and milk. The current program will benefit from our laboratory's veterinary diagnostic experience, expertise, and infrastructure that we will use to accomplish the work described for this project. In addition to addressing the current need for added laboratory capacity in the event of a large-scale outbreak or threat incident involving animal food or drug-related illnesses or other large-scale emergency events requiring surge capacity testing, the PADLS New Bolton Center Laboratory can further strengthen the Vet-LRN through diagnostic activities that better enable early detection of emerging events involving national food safety and security and facilitate the rapid responses that can minimize harm and best protect both human and animal health. Our laboratory provides comprehensive veterinary diagnostic services to the Commonwealth of Pennsylvania and the surrounding region. Some analyses are requested as part of normal surveillance activities or routine necropsies, while others are associated with cases of excessive, unexpected, or otherwise unexplainable animal losses or illness. The laboratory is fully accredited by AAVLD and adheres to their ^Requirements for an Accredited Veterinary Medical Diagnostic Laboratory_, meeting specific requirements pertaining to all aspects of the laboratory and its activities. AAVLD also requires that our laboratory has a Quality System in place that documents policies, systems, programs, and procedures. Due to the varied nature of the sample matrices we receive we are constantly improving and refining our analytical methods in order to ensure their sensitivity and specificity. We are confident in our ability to support the Vet-LRN in this project due to our present qualifications and experience. 1