Storage and Distribution of Chemicals and Drugs for Preclinical Eval and Developm

用于临床前评估和开发的化学品和药物的储存和分配

• 批准号: 8654916
• 负责人: DOUG SMALLWOOD
• 金额: $ 66.42万
• 依托单位: FISHER BIOSERVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8654916
• 关键词: Area; Basic Science; Biological; Biological Factors; Chemicals; Communities; Contracts; Databases; Development; Documentation; Equipment and supply inventories; Maintenance; Malignant Neoplasms; Pharmaceutical Preparations; Preclinical Testing; Regulation; Research; Sampling; Therapeutic; United States National Institutes of Health; Update; anti-cancer therapeutic; oncology; pre-clinical; programs; screening; small molecule

The principal functions of this contract are the acquisition, storage and distribution of small molecule organic compounds for preclinical testing in both NCI anticancer programs and in programs within the external research community. Samples are received and distributed both domestically and internationally. The contract provides for safe and efficient receipt, storage, inventory, distribution, plating, disposal and documentation of synthetic compounds, purified natural products and also a limited number of bulk GMP drugs. These tasks must be executed in compliance with all local, state and Federal regulations. This contract is also responsible for the management of compound supplier information, correspondence to and from the compound suppliers, for maintenance and updating chemical databases, systematic file and record keeping and reacquisition of samples for continuing chemical and/or biological studies. The contract may also support other NIH programs outside the oncology area, e.g. NIH-RAID, in a limited manner.

该合同的主要职能是获取、储存和分配小分子有机化合物，用于NCI抗癌计划和外部研究社区计划的临床前试验。样品在国内和国际上都被接收和分发。该合同规定安全和有效地接收、储存、库存、分配、电镀、处理和记录合成化合物、纯化的天然产品以及数量有限的原料药。这些任务的执行必须遵守所有地方、州和联邦法规。该合同还负责化合物供应商信息的管理、化合物供应商的往来通信、维护和更新化学数据库、系统档案和记录保存以及为继续进行化学和/或生物研究而重新获取样品。该合同还可能以有限的方式支持肿瘤学领域以外的其他NIH项目，例如NIH-RAID。