Storage and Distribution of Chemicals and Drugs for Preclinical Eval and Developm
Storage and Distribution of Chemicals and Drugs for Preclinical Eval and Developm
批准号:
8654916
负责人:
DOUG SMALLWOOD
金额:
$66.42万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-03-01 至 2013-05-31
关键词:
AreaBasic ScienceBiologicalBiological FactorsChemicalsCommunitiesContractsDatabasesDevelopmentDocumentationEquipment and supply inventoriesMaintenanceMalignant NeoplasmsPharmaceutical PreparationsPreclinical TestingRegulationResearchSamplingTherapeuticUnited States National Institutes of HealthUpdateanti-cancer therapeuticoncologypre-clinicalprogramsscreeningsmall molecule
中文摘要
该合同的主要功能是在NCI抗癌项目和外部研究社区的项目中获得、储存和分发用于临床前测试的小分子有机化合物。在国内和国际上接收和分发样品。该合同规定安全有效地接收、储存、库存、分配、电镀、处置和记录合成化合物、纯化天然产品以及数量有限的GMP散装药物。这些任务的执行必须符合所有地方、州和联邦法规。该合同还负责管理化合物供应商信息、化合物供应商往来信函、维护和更新化学数据库、系统文件和记录保存以及重新获取样品以继续进行化学和/或生物学研究。该合同还可能以有限的方式支持肿瘤学领域以外的其他NIH项目,例如NIH-RAID。
英文摘要
The principal functions of this contract are the acquisition, storage and distribution of small molecule organic compounds for preclinical testing in both NCI anticancer programs and in programs within the external research community. Samples are received and distributed both domestically and internationally. The contract provides for safe and efficient receipt, storage, inventory, distribution, plating, disposal and documentation of synthetic compounds, purified natural products and also a limited number of bulk GMP drugs. These tasks must be executed in compliance with all local, state and Federal regulations. This contract is also responsible for the management of compound supplier information, correspondence to and from the compound suppliers, for maintenance and updating chemical databases, systematic file and record keeping and reacquisition of samples for continuing chemical and/or biological studies. The contract may also support other NIH programs outside the oncology area, e.g. NIH-RAID, in a limited manner.
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Title: Registration, Storage and Distribution of Chemicals and Drugs for Pre-Clinical Discovery, Evaluation and Development
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项目类别:
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负责人:DOUG SMALLWOOD
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依托单位:
海外基金