NIAMS Multidisciplinary Clinical Research Center

NIAMS多学科临床研究中心

• 批准号: 8501776
• 负责人: Leena Sharma
• 金额: $ 100.53万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-01 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8501776
• 关键词: Address; Algorithms; Awareness; Cartilage; Clinical Research; Clinical Sciences; Cohort Studies; Collaborations; Communities; Development; Environment; Evaluation; Funding; Goals; Healthcare; Institutes; Institution; Interdisciplinary Study; Knee; Knowledge; Medical; Medicine; Methodology; Modeling; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Outcome; Physical activity; Positioning Attribute; Prevention; Preventive Medicine; Prosthesis; Public Health; Quality of life; Rehabilitation therapy; Research; Research Personnel; Resources; Rheumatism; Rheumatoid Arthritis; Rheumatology; Secure; Social Sciences; Solutions; Translational Research; Universities; Work; base; cost; data management; medical schools; multidisciplinary; orthotics; public health relevance

DESCRIPTION (provided by applicant): The goals of the Northwestern University (NU) Multidisciplinary Clinical Research Center (MCRC) are to: 1) conduct cutting-edge research aimed at the prevention or control of rheumatic diseases and poor outcomes associated with these conditions; 2) provide the academic environment that a) supports the multidisciplinary research of MCRC investigators, and b) organizes and galvanizes rheumatic disease research at NU. The current MCRC at NU operates as an integrated unit to address a broad range of clinical research endeavors. The MCRC continues to unite the NU Feinberg School of Medicine Division of Rheumatology in the Department of Medicine, the Department of Preventive Medicine, and the Institute for Healthcare Studies, as well as the NU Clinical and Translational Sciences Institute (NUCATS, NU's CTSA entity). The proposed new cycle of our MCRC illustrates the strength of these relationships and new collaboration development with the Department of Medical Social Sciences and the NU Prosthetics and Orthotics Center. As this application will show, we have an outstanding, well-organized research base as well as unique institutional resources that we incorporate and leverage. In turn, our Center continues to enrich the environment by developing new resources for our institution. The proposed new cycle of the NU MCRC includes an Administrative Core, a Methodology/Data Management Core, and 3 projects: Project 1: Physical Activity Changes & Thresholds: Quality of Life and Outcomes in Knee 0A; Project 2: Defining Targets for Therapy to Delay Cartilage Loss and Poor Outcome in Knee OA; Project 3: Evaluation of an Algorithm to Detect Rheumatoid Arthritis Cases in Cohort Studies. The specific objectives of this proposal are to: secure funding for these 2 Cores and 4 projects; to leverage this MCRC funding to further enhance rheumatic disease research at NU; and to participate in the national effort to increase awareness within the academic community and the community at large of the public health burden of the rheumatic diseases and the possible public health, medical, and rehabilitative solutions for these conditions and their consequences. We are strongly positioned to complete the work we propose and to continue to serve as an organizational and scientific focus to energize rheumatic disease research at NU.

描述(由申请人提供)：西北大学多学科临床研究中心(MCRC)的目标是：1)开展旨在预防或控制风湿病和与这些疾病相关的不良结果的尖端研究；2)提供学术环境，a)支持MCRC研究人员的多学科研究，b)在NU组织和鼓励风湿病研究。目前NU的MCRC作为一个综合单位运作，以解决广泛的临床研究努力。MCRC继续联合NU Feinberg医学院、医学系风湿病学部、预防医学系和医疗研究所，以及NU临床和翻译科学研究所(NUCATS，NU的CTSA实体)。我们的MCRC拟议的新周期表明了这些关系的力量以及与医学社会科学系和NU假肢和矫形中心的新合作发展。正如这份申请所显示的那样，我们拥有一个出色的、组织良好的研究基地以及独特的机构资源，我们可以并入和利用这些资源。反过来，我们的中心通过为我们的机构开发新的资源来继续丰富环境。NU MCRC的拟议新周期包括一个行政核心、一个方法/数据管理核心和3个项目：项目1：体力活动变化和阈值：膝关节0A的生活质量和结果；项目2：确定延缓膝关节骨关节炎软骨丢失和不良结果的治疗目标；项目3：在队列研究中评估发现类风湿性关节炎病例的算法。这项建议的具体目标是：确保为这2个核心和4个项目提供资金；利用MCRC的这笔资金进一步加强诺大的风湿病研究；并参与国家努力，提高学术界和广大社区对风湿病的公共卫生负担以及针对这些疾病及其后果可能的公共卫生、医疗和康复解决方案的认识。我们很有能力完成我们提出的工作，并继续作为组织和科学的重点，为NU的风湿病研究注入活力。