Northwestern University Clinical and Translational Science Institute (NUCATS)

西北大学临床与转化科学研究所 (NUCATS)

• 批准号: 10650727
• 负责人: Leena Sharma
• 金额: $ 93.16万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-12 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10650727
• 关键词: Academia; Appointment; Area; Clinical Sciences; Clinical Trials; Collaborations; Communities; Data; Disparate; Dissemination and Implementation; Diverse Workforce; Doctor of Philosophy; Education; Future; Goals; Government; Grant; Individual; Industry; Intervention; Laboratories; Mentors; Outcome Measure; Program Development; Publications; Records; Research; Research Personnel; Research Project Grants; Resource Development; Resources; Science; Testing; Training; Training and Education; Translational Research; United States Agency for Healthcare Research and Quality; United States National Institutes of Health; Universities; Vocational Guidance; career development; design; experience; falls; improved; innovation; peer coaching; programs; success; training opportunity; translational genomics

ABSTRACT: NUCATS began our KL2 program in 2008, along with numerous other programs to support K scholars across our hub. The 25 KL2 scholars who have participated in the program include 11 MDs, 8 MD/PhDs and 7 PhDs, whose research areas span laboratory-based translational discovery, outcome measures testing, genomic translation, clinical trials, and community-level interventions. As of fall 2018, 21 KL2 scholars have completed the program. The progress of the KL2 program at NU has been outstanding. The scholars' publication and grant records are exceptional. Seventy-five percent (15/21) of those who completed the program have received individual or independent NIH, DHHS, or AHRQ grant support, including 3 K08s, 1 K22, 5 K23s, 12 R01s, 2 R03s, 1 R18, 1 R21, and 1 R34 Furthermore, 85% of those who have completed the program received NIH support as a PI or a significant contributor, while 90% have received some form of NIH or non-NIH grant support. Subsequent to their appointment periods, our scholars have received a combined total of over $45 million in direct research grants as PIs. Approximately 704 publications (mean 34), as author or co-author, have been attributed to the 21 scholars who have completed the program, after they joined the KL2 program. These data document a strong and sustained impact of the NUCATS KL2 Career Development Program on the CTS community. Closely aligned with the overall goals of NUCATS, we will now build on our outstanding legacy and enhance our impact through three initiatives, by: refining our proven programs, which are based on robust mentoring teams and designed around the educational needs of individual scholars to provide them with optimal, personalized career development opportunities; providing career development resources including formal courses, peer mentoring and systematic career guidance to scholars across disparate areas of expertise; and integrating collaboration, training and resources for scholars, including opportunities for training in team science and community implementation and dissemination, for research experiences in academia, government and industry, and for interactions with other local CTSAs.

摘要：NUCATS于2008年开始了我们的KL 2项目，沿着的还有许多其他项目来支持K 我们中心的学者参加该计划的25名KL 2学者包括11名医学博士，8名 MD/博士和7名博士，其研究领域涵盖基于实验室的转化发现，成果 测量测试，基因组翻译，临床试验和社区干预措施。截至2018年秋季， KL 2学者已经完成了该计划。NU的KL 2计划的进展非常出色。 学者的出版物和赠款记录是例外。75%（15/21）的人 已完成该计划的人已获得个人或独立的NIH，DHHS或AHRQ资助支持，包括 3个K 08、1个K22、5个K23、12个R 01、2个R 03、1个R18、1个R21和1个R34。 完成该计划的人作为PI或重要贡献者获得了NIH的支持，而90%的人获得了 一些形式的NIH或非NIH资助。在他们的任期结束后，我们的学者 作为独立研究员，获得了总计超过4500万美元的直接研究赠款。704篇论文 (mean 34），作为作者或合著者，已被归因于谁已经完成了该计划的21名学者， 在他们加入KL 2计划后这些数据记录了NUCATS KL 2的强大而持续的影响 CTS社区的职业发展计划。与NUCATS的总体目标紧密结合，我们 现在，我们将在我们杰出的遗产基础上，通过三项举措加强我们的影响力： 经过验证的项目，基于强大的指导团队并围绕以下人员的教育需求设计 个别学者为他们提供最佳的，个性化的职业发展机会;提供 职业发展资源，包括正规课程、同侪辅导和系统的职业指导， 学者在不同的专业领域;和整合协作，培训和资源的学者， 包括团队科学和社区实施和传播方面的培训机会， 在学术界，政府和工业界的研究经验，并与其他地方CTSA的互动。

项目成果

Application of Guideline-Based Echocardiographic Assessment of Left Atrial Pressure to Heart Failure with Preserved Ejection Fraction.

• DOI: 10.1016/j.echo.2020.12.008
• 发表时间: 2021-05
• 期刊: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
• 作者: Rethy L;Borlaug BA;Redfield MM;Oh JK;Shah SJ;Patel RB
• 通讯作者: Patel RB

Multidisciplinary approach to cardiac and pulmonary vascular disease risk assessment in liver transplantation: An evaluation of the evidence and consensus recommendations.

• DOI: 10.1111/ajt.14531
• 发表时间: 2018-01
• 期刊: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
• 作者: VanWagner LB;Harinstein ME;Runo JR;Darling C;Serper M;Hall S;Kobashigawa JA;Hammel LL
• 通讯作者: Hammel LL

Timing Deficits in ADHD: Insights From the Neuroscience of Musical Rhythm.

• DOI: 10.3389/fncom.2018.00051
• 发表时间: 2018
• 期刊: Frontiers in computational neuroscience
• 影响因子: 3.2
• 作者: Slater JL;Tate MC
• 通讯作者: Tate MC

Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice.

• DOI: 10.1093/hmg/ddac087
• 发表时间: 2022-08-25
• 期刊: Human molecular genetics
• 影响因子: 3.5

Motor Optimality Scores are significantly lower in a population of high-risk infants than in infants born moderate-late preterm.

• DOI: 10.1016/j.earlhumdev.2022.105684
• 发表时间: 2022-11
• 期刊: EARLY HUMAN DEVELOPMENT
• 影响因子: 2.5
• 作者: Peyton, Colleen;Millman, Ryan;Rodriguez, Sarah;Boswell, Lynn;Naber, Meg;Spittle, Alicia;de Regnier, RayeAnn;Barbosa, Vanessa Maziero;Sukal-Moulton, Theresa
• 通讯作者: Sukal-Moulton, Theresa