Interdisciplinary Training in Pain Research

疼痛研究跨学科培训

• 批准号: 8881335
• 负责人: DONNA L HAMMOND
• 金额: $ 20.56万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8881335
• 关键词: Pain Research; Training

DESCRIPTION (provided by applicant): Chronic pain is a significant issue in health care delivery, affecting 116 million Americans at a conservative cost of $560 billion. This application seeks renewal of support for an interdisciplinary training program in pain research at the University of Iowa. The program has been highly successful in terms of increasing collaborations among trainers and mentoring pre- and postdoctoral trainees of exemplary quality to independent funding and careers. The program will continue to study the cellular, molecular, pharmacological, physiological and anatomical mechanisms that subserve acute and chronic pain while further strengthening the clinical and translational work begun during the previous award. The 16 core program faculty are NIH-funded investigators with complementary expertise in the fields of molecular, cellular and systems neurobiology. They comprise a balanced representation of basic and physician scientists, as well as bench and patient-based research. Each trainer has a strong record of training both predoctoral and postdoctoral fellows and will also mentor a subset of junior trainers of great promise. Support is requested for two predoctoral and two postdoctoral trainees for this award period. In line with our goal to strengthen translational research, the postdoctoral positions will be primarily targeted for MD, MD/PhD, PT/PhD or DPT trainees, but will also accept PhD trainees with a strong interest in translational research. These individuals will benefit from a period of protected time to learn the elements of research and/or to restart their research programs in advance of a faculty level appointment. Two nurse scientists continue as adjunct trainers to pursue collaborations in clinical and translational research programs developed in the last award period. In the next funding period, the program proposes to build a stronger relationship with members of the Institute for Clinical and Translational Science who have expertise in patient-centered outcomes research and comparative effectiveness research. This approach will recruit new faculty to the training program and increase attractiveness to clinicians. The training program provides a highly structured and diverse program of didactic coursework, including monthly seminars, weekly journal clubs and biweekly work-in-progress meetings, that is coupled with research training in a highly collaborative and inter-active environment. All courses, as well as mechanisms of interaction and trainee evaluation are established. The overall goal of the training program is to provide our trainees with (1) an individualized curriculum that provide a solid knowledge base appropriate to their career plans; (2) rigorous training in the elements of scientific investigation including the formulation of research hypotheses, experimental design and analysis; (3) mastery of two to three research techniques; (4) opportunities to develop their verbal communication skills; (5) experience in the construction of manuscripts and grant proposals; and (6) the ability to interact and collaborate with basic and clinical investigators boh within and outside the institution who are actively engaged in research. Trainees in this program will acquire the knowledge, experience, and skill sets necessary for successful transition to an independent research career in academia, industry or government.

慢性疼痛是医疗保健服务中的一个重要问题，影响了1.16亿美国人，保守的成本为5600亿美元。本申请寻求对爱荷华州大学疼痛研究跨学科培训项目的支持。该计划在增加培训师之间的合作和指导具有示范性质量的博士前和博士后学员到独立资金和职业方面非常成功。该计划将继续研究有助于急性和慢性疼痛的细胞，分子，药理学，生理和解剖机制，同时进一步加强前一个奖项期间开始的临床和转化工作。16名核心项目教师是NIH资助的研究人员，在分子，细胞和系统神经生物学领域具有互补的专业知识。他们包括基础和医生科学家的平衡代表，以及板凳和病人为基础的研究。每位培训师都有很好的博士前和博士后培训记录，也将指导一部分有前途的初级培训师。在本奖学金期间，需要为两名博士前和两名博士后学员提供支助。根据我们加强翻译研究的目标，博士后职位将主要针对MD，MD/PhD，PT/PhD或DPT学员，但也将接受对翻译研究有浓厚兴趣的博士学员。这些人将受益于一段受保护的时间来学习 研究的元素和/或重新启动他们的研究计划提前一个教师水平的任命。两名护士科学家继续作为兼职培训师，在上一个奖项期间开发的临床和转化研究项目中进行合作。在下一个资助期内，该计划建议与临床和转化科学研究所的成员建立更牢固的关系，这些成员在以患者为中心的结果研究和比较有效性研究方面具有专业知识。这种方法将为培训计划招募新的教师，并增加对临床医生的吸引力。该培训计划提供了一个高度结构化和多样化的教学课程计划，包括每月研讨会，每周期刊俱乐部和双周工作进展会议，这是在一个高度协作和互动的环境中与研究培训相结合。所有课程以及互动和学员评价机制都已建立。培训计划的总体目标是为我们的学员提供（1）个性化的课程，为他们的职业规划提供坚实的知识基础;（2）严格的科学调查要素培训，包括制定研究假设，实验设计和分析;（3）掌握两到三种研究技术;（4）发展口头沟通技巧的机会;（5）培养他们的语言能力。（5）在手稿和赠款提案建设的经验;和（6）互动和合作的能力，与基础和临床研究人员BOH内外的机构谁是积极从事研究。该计划的学员将获得成功过渡到学术界，工业界或政府独立研究职业所需的知识，经验和技能。