Investigating Obesity and Chronic Disease-Related Risk Factors of Alaska Natives

调查阿拉斯加原住民的肥胖和慢性病相关危险因素

• 批准号: 8883578
• 负责人: BERT Brandon BOYER
• 金额: $ 102.49万
• 依托单位: UNIVERSITY OF ALASKA FAIRBANKS
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-15 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8883578
• 关键词: Achievement; Address; Adopted; Advisory Committees; Alaska; Alaska Native; Americas; Area; Award; Awareness; Behavioral Genetics; Businesses; Capital; Centers of Research Excellence; Chronic Disease; Clinical Research; Committee Members; Communication; Communities; Community Relations; Comorbidity; Consultations; Core Facility; Development; Disease; Ensure; Ethics; Evidence based practice; Evolution; Extramural Activities; Faculty; Fees; Fostering; Funding; Future; Goals; Grant; Health; Health Policy; Incidence; Income; Individual; Institution; Interdisciplinary Study; Intervention; Intervention Studies; Investments; Laboratories; Lead; Leadership; Learning; Mentors; Metabolic Diseases; Minority; Names; Native-Born; Nutritional; Obesity; Outcomes Research; Participant; Personal Satisfaction; Phase; Pilot Projects; Population; Prevention; Preventive; Process; Publications; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Risk; Risk Factors; Rural; Scientist; Source; Strategic Planning; Substance abuse problem; Suicide; Testing; Training; Translational Research; Trust; United States National Institutes of Health; Universities; Work; Youth; base; community based participatory research; design; disorder risk; evidence base; experience; health disparity; improved; innovation; member; minority health; next generation; obesity treatment; professor; programs; ranpirnase; social; success; tribal community

The Center for Alaska Native Health Research (CANHR), established in 2001 with COBRE I support, has become nationally recognized for both the quality of its research to reduce disease and promote health among Alaska Native (AN) people and for Community-Based Participatory Research (CBPR) with minority populations. AN people have been engaged in all phases of CANHR research, including setting CANHR's current research agenda on obesity and metabolic disease. The evolution and solidification of this decade-long community partnership has expanded this research agenda into intervention research aimed at prevention and treatment of obesity and metabolic disease, youth suicide, and substance abuse. CANHR funding has increased from one NIH grant in 2001, to nearly $5M in 2010. With support from an NIH construction grant, we are building the first two clinical research laboratories in the state of Alaska, while increasing our net space by over 5,000 sq. ft. The University of Alaska Fairbanks leadership has increased its already substantial commitment to CANHR, further augmenting our research expertise with new faculty hires and consultation from nationally recognized senior researchers through the President's Professors program. Our publication rate continues to increase, surpassing 100 publications in the past four years. The goal of the proposed COBRE Phase III Transitional Center is to solidify these achievements with a focus on transitioning CANHR into a self-supporting, sustainable, nationally recognized research center focused on AN health and CBPR. We propose to do this by: (1) strengthening the infrastructure of core resources to support research and community engagement; (2) expanding mentoring and training opportunities to develop the next generation of AN health researchers; (3) developing an innovative Pilot Project program (External Partnerships for Specific Expertise), to foster collaborative research with scientific leaders at research-intensive institutions that, in our experience, will p9sitively impact our extramural funding success; (4) continuing the President's Professors Program to expand intellectual capital and national recognition of CANHR; and (5) including a comprehensive business plan to ensure income to sustain CANHR cores.

阿拉斯加原住民健康研究中心 (CANHR) 于 2001 年在 COBRE I 的支持下成立，因其在阿拉斯加原住民 (AN) 中减少疾病和促进健康的研究质量以及针对少数族裔的社区参与性研究 (CBPR) 的质量而获得全国认可。 AN人参与了CANHR研究的各个阶段，包括制定CANHR当前关于肥胖和代谢疾病的研究议程。这一长达十年的社区伙伴关系的演变和巩固已将这一研究议程扩展到旨在预防和治疗肥胖和代谢疾病、青少年自杀和药物滥用的干预研究。 CANHR 的资金已从 2001 年 NIH 的一项拨款增加到 2010 年的近 500 万美元。在 NIH 建设拨款的支持下，我们正在阿拉斯加州建造首批两个临床研究实验室，同时将我们的净空间增加超过 5,000 平方英尺。阿拉斯加大学费尔班克斯分校的领导层增加了对 CANHR 的本已实质性的承诺，通过聘用新的教员和获得国家认可的高级专家的咨询，进一步增强我们的研究专业知识。 研究人员通过总统教授计划。我们的发表率持续增加，在过去四年中超过了 100 种出版物。拟议的 COBRE 第三阶段过渡中心的目标是巩固这些成就，重点是将 CANHR 转变为一个自给自足、可持续、国家认可的研究中心，重点关注 AN 健康和 CBPR。我们建议通过以下方式做到这一点：（1）加强核心资源基础设施，以支持研究和社区参与； (2) 扩大指导和培训机会，以培养下一代 AN 健康研究人员； (3) 制定创新的试点项目计划（特定专业知识的外部合作伙伴关系），以促进与研究密集型机构的科学领导者的合作研究，根据我们的经验，这将对我们的外部资助成功产生积极影响； (4) 继续开展校长教授计划，以扩大 CANHR 的智力资本和国家认可度； (5) 包括一项全面的业务计划，以确保维持 CANHR 核心的收入。