Core Center for Communication Disorders

描述（由申请人提供）：沟通障碍核心中心（CCCD）将通过在三个领域提供核心支持，提高合格研究人员的效率，促进男孩镇国家研究医院（BTNRH）和邻近学术机构的广泛研究项目之间的合作。实验室计算和生物统计核心（LCBC），在斯蒂芬·尼利的指导下，将继续支持研究项目：1)提供故障排除和软件开发，使研究生产力；2)开发和维护有益于多个实验室的有用软件包；3)在研究硬件和软件的使用方面提供专家协助。随着生物统计资源的增加，LCBC将为所有CCCD研究项目提供基本服务。在Barbara Morley和Mary Pat Moeller的指导下，新的研究协同核心（RSC）将通过以下方式促进BTNRH和邻近机构的大量研究人员之间的互动：1)通过多方面的跨学科研究和信息共享计划促进科学合作；2)通过建立亲和团体，促进新思想和研究技术的融合；3)通过确定资源共享和其他形式的实验室和机构之间相互依赖的机会来减少合作的障碍。在Michael Gorga的指导下，人类研究受试者核心（HRSC）将继续通过以下方式支持人类受试者的研究：1)通过维护和扩大表示有兴趣参与研究的个人数据库，提高招募潜在受试者（包括少数民族受试者）的效率；2)协助调查人员确保其符合当地和国家的规定；3)协助研究者准备IRB方案、IRB和NIH进展报告，并妥善保管和处理同意书及相关文件。目前CCCD的用户群包括9个r01拨款，但BTNRH和邻近机构还有20多名额外的研究人员，他们有NIH资助的历史，并对沟通障碍研究感兴趣，可以为提高效率和有效合作提供必要的临界质量。

DESCRIPTION (provided by applicant): The Core Center for Communication Disorders (CCCD) will increase the efficiency of qualifying investigators and promote collaboration among a wide range of research programs at the Boys Town National Research Hospital (BTNRH) and neighboring academic institutions by providing Core support in three areas. The Laboratory Computing and Biostatistics Core (LCBC), under the direction of Stephen Neely, will continue to support research programs by: 1) providing troubleshooting and software development that enables research productivity; 2) developing and maintaining useful software packages that benefit multiple laboratories; and 3) providing expert assistance in the use of research hardware and software. With the addition of a biostatistics resource, the LCBC will provide essential services to all CCCD research programs. The new Research Synergy Core (RSC), under the direction of Barbara Morley and Mary Pat Moeller, will facilitate interactions within a large group of investigators at BTNRH and neighboring institutions by: 1) fostering scientific collaboration through a multifaceted, interdisciplinary program of research and information sharing; 2) fostering the integration of new ideas and research technologies by establishing affinity groups; and 3) reducing barriers to collaboration by identifying opportunities for resource sharing and other forms of interdependence across laboratories and institutions. The Human Research Subjects Core (HRSC), under the direction of Michael Gorga, will continue to support research with human subjects by: 1) increasing the efficiency, with which potential subjects are recruited, including minority subjects, by maintaining and expanding a database of individuals who have expressed an interest in participating in research; 2) assisting investigators in assuring that they are in compliance with local and national regulations; and 3) assisting investigators in the preparation of IRB protocols, IRB and NIH progress reports and in the proper storage and handling of consent forms and related documents. The current CCCD user base includes nine R01grants, but there are more than 20 additional investigators at BTNRH and neighboring institutions with a history of NIH funding and an interest in communication disorders research that can provide the critical mass necessary for increased efficiency and effective collaborations.