权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Mild Cognitive Impairment in Older Rural Dwelling Adults

农村老年人的轻度认知障碍

基本信息

批准号：
8926706
负责人：
Meghan K Mattos
金额：
$ 4.31万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-09-01 至 2017-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8926706
关键词：
Address Adult Affect Alzheimer&apos s Disease Appalachian Region Area Attention Boxing Cardiovascular Diseases Cerebrovascular Disorders Chronic Disease Clinical Cognition Cognitive Complex Cross-Sectional Studies Data Data Analyses Data Set Dementia Detection Development Diabetes Mellitus Diagnosis Disease Disease Progression Early Intervention Educational process of instructing Elderly Environmental Health Evaluation Faculty Fellowship Foundations Future Future Generations Goals Health Health Promotion Health Services Accessibility Healthy People 2020 Home environment Impaired cognition Incidence Intervention Interview Language Lead Life Literature Maintenance Measures Memory Methodology Modeling Nurses Outcome Participant Patients Perception Persons Population Positioning Attribute Postdoctoral Fellow Prevalence Preventive Intervention Process Qualitative Methods Recruitment Activity Research Resources Rest Risk Risk Factors Rural Rural Health Sampling Science Scientist Secondary Prevention Severities Speed Sum Symptoms Syndrome System Therapeutic Intervention Time Universities Vulnerable Populations base cerebrovascular cognitive change disability executive function health disparity health equity improved innovation insight interest mild cognitive impairment novel phase 1 study population health prevent programs public health relevance residence rural area rural disparities screening social social health determinants therapy development

项目摘要

DESCRIPTION (provided by applicant): Although more than 20% of the US population live in rural areas, this is an underserved and understudied population. Rural adults suffer disproportionately poorer health and worse health outcomes compared with the rest of the nation. Considerably less research has focused on cognitive health outcomes and their risk factors among older, rural dwelling adults. Among these cognitive changes is mild cognitive impairment (MCI), a condition that affects as many as 19% of older US adults and is widely recognized as a risk state for Alzheimer's Disease and other dementias. As such, MCI represents a key target for interventions aimed at the secondary prevention of dementia. We have reason to believe that older, rural adults are especially vulnerable to MCI, based on known higher rates of factors associated with the syndrome. Complicating matters, limited resources and access to care may lead to delayed detection of cognitive changes, making rural adults an especially vulnerable group that is possibly deprived of opportunities for screening and early intervention in the disease process. Based on known rural health disparities, especially later diagnosis of chronic diseases, it is reasonable to hypothesize that MCI may present later in its course in rural adults, but studies describing older, rural dwelling adults with MCI are absent from the literature. The primary purpose of this study is to determine if rural residence is a unique risk factor for delayed detection of MCI. This novel study will examine MCI symptom severity and qualitative description to gain insight into rural cognitive health. The study seeks t advance the science by improving the understanding of MCI in a vulnerable population, which may ultimately direct the development of future health promotion research.

描述(申请人提供)：虽然超过20%的美国人口生活在农村地区，但这是一个服务不足和研究不足的人口。与全国其他地区相比，农村成年人的健康状况更差，健康状况也更差。相当少的研究集中在农村老年人的认知健康结果及其风险因素上。这些认知变化包括轻度认知障碍(MCI)，这是一种影响多达19%的美国老年人的疾病，被广泛认为是阿尔茨海默氏症和其他痴呆症的风险状态。因此，MCI是旨在二级预防痴呆症的干预措施的关键目标。我们有理由相信，基于已知的与MCI相关因素的较高比率，农村老年人尤其容易患上MCI。更复杂的情况是，有限的资源和获得护理的机会可能导致认知变化的延迟检测，使农村成年人成为特别脆弱的群体，可能被剥夺在疾病过程中进行筛查和早期干预的机会。基于已知的农村健康差异，特别是慢性病的后期诊断，可以合理地假设MCI可能在稍后的过程中出现在农村成年人身上，但文献中没有描述患有MCI的老年农村居民的研究。这项研究的主要目的是确定农村居住地是否是延迟发现MCI的唯一危险因素。这项新颖的研究将检查MCI症状的严重性和定性描述，以深入了解农村认知健康。这项研究试图通过提高对弱势人群对MCI的理解来推进这一科学，这可能最终指导未来健康促进研究的发展。