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Investigation of the Molecular Basis of Frailty and Development of Frailty Biomarkers in a Novel Mouse Ageing Model

Investigation of the Molecular Basis of Frailty and Development of Frailty Biomarkers in a Novel Mouse Ageing Model
在新型小鼠衰老模型中研究衰弱的分子基础和衰弱生物标志物的开发
批准号:
nhmrc : 1122542
负责人:
Ms Alice Kane
金额:
$27.81万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2021-12-31

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中文摘要
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英文摘要
Frailty is a state of high vulnerability for adverse health outcomes, and the prevalence of frailty increases with increasing age. There is very little known about why frailty develops, and there is also no widely accepted, efficient method of determining if someone is frail. This project will test blood markers for frailty, that will allow for optimization of treatment for older frail people and use mouse models of frailty to learn more about why frailty develops.
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Investigation of the Molecular Basis of Frailty and Development of Frailty Biomarkers in a Novel Mouse Ageing Model
  • 批准号:
    nhmrc : GNT1122542
  • 项目类别:
    Early Career Fellowships
  • 资助金额:
    $40.88万
  • 财政年份:
    2017
  • 负责人:
    Ms Alice Kane
  • 依托单位:
The Role of mTOR in the Ageing Liver: Implications for Paracetamol Hepatotoxicity
  • 批准号:
    nhmrc : 1038169
  • 项目类别:
    Postgraduate Scholarships
  • 资助金额:
    $6.17万
  • 财政年份:
    2012
  • 负责人:
    Ms Alice Kane
  • 依托单位:
国内基金
海外基金
Kidney injury molecular(KIM-1)介导肾小管上皮细胞自噬在糖尿病肾病肾间质纤维化中的作用
  • 批准号:
    81300605
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    23.0万元
  • 批准年份:
    2013
  • 负责人:
    唐琳
  • 依托单位:
Molecular Plant
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
Molecular Plant