The Autism Impact Measure: A New Tool for Treatment Outcome Measurement

自闭症影响测量：治疗结果测量的新工具

• 批准号: 8911366
• 负责人: STEPHEN M KANNE
• 金额: $ 124.74万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-13 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8911366
• 关键词: Aftercare; Age; Area; Autistic Disorder; Behavior Therapy; Child; Clinical Research; Cognitive; Communities; Data; Development; Disease; Economics; Factor Analysis; Family; Focus Groups; Frequencies; Goals; Health; Health Services; Intervention; Interview; Knowledge; Measurement; Measures; Methods; National Institute of Child Health and Human Development; National Institute of Mental Health; National Institute of Neurological Disorders and Stroke; Outcome; Outcome Assessment; Outcome Measure; Outcomes Research; Pattern; Pharmacological Treatment; Phase; Policy Maker; Population; Process; Property; Provider; Psychometrics; Qualitative Methods; Recording of previous events; Reporting; Research; Research Personnel; Risk; Sampling; Site; Structure; Symptoms; Time; Treatment Effectiveness; Treatment outcome; Ultrasonography; Validity and Reliability; autism spectrum disorder; clinical care; clinical practice; cost; design; experience; improved; meetings; novel; novel strategies; programs; psychosocial; response; teacher; tool; trait; treatment duration; treatment effect

DESCRIPTION (provided by applicant): Studies of behavioral and pharmacological treatments for autism spectrum disorders (ASD) are increasing at a rapid pace. However, demonstration of treatment effects has been limited by a lack of psychometrically sound measurement tools that are sensitive to change in core symptoms of ASD. In order to meet this need, the current team of researchers has developed a new tool, the Autism Impact Measure (AIM), which uses a novel approach designed to be sensitive to incremental changes in ASD symptoms. Unlike existing ASD measures, the AIM assesses the frequency of symptom occurrence using a 2-week recall period and a 5-point response format, allowing the measure to track incremental change over shorter periods of time. In addition, the AIM assesses the impact of ASD symptoms, allowing for identification of symptoms that have the most significant impact on actual functioning. This novel two-pronged approach has the potential to inform both treatment outcome research and clinical practice. Preliminary results from our initial multi-site study of psychometric properties indicate strong reliability and validity. The aims of the current project are 1) to further examine construct validity, 2) to examine the measure's sensitivity to change following treatment, and 3) to begin development of a modified teacher-report version. Data will be collected across three sites nationwide, and sensitivity to change will be established by collecting data pre-, during, and post-treatment among three different well-established treatments for ASD. The proposed team of investigators is well-poised to conduct this project, and includes a national network of collaborators with a proven track-record of multi-site ASD research and expertise in measure development and psychometrics. The AIM represents a novel measurement approach in the autism field and is highly relevant to clinical care and research. A major goal across federal health agencies is to improve the lives of children with ASD by developing interventions that target core symptoms of the disorder, and the development of a reliable and valid treatment-outcome measure has the potential to enhance the pace of treatment-outcome research.

描述（由申请人提供）：自闭症谱系障碍（ASD）的行为和药物治疗研究正在迅速增加。然而，由于缺乏对ASD核心症状变化敏感的心理测量学上可靠的测量工具，治疗效果的证明受到限制。为了满足这一需求，目前的研究团队开发了一种新的工具，自闭症影响测量（AIM），它采用了一种新的方法，旨在对ASD症状的增量变化敏感。与现有的ASD测量方法不同，AIM使用2周的回忆期和5点回答格式来评估症状发生的频率，允许测量在较短的时间内跟踪增量变化。此外，AIM评估ASD症状的影响，允许识别对实际功能有最显著影响的症状。这种新颖的双管齐下的方法有可能为治疗结果研究和临床实践提供信息。我们最初的多地点心理测量特性研究的初步结果显示了很强的信度和效度。当前项目的目的是1)进一步检查结构效度，2)检查测量对处理后变化的敏感性，以及3)开始开发修改后的教师报告版本。数据将在全国三个地点收集，并建立对变化的敏感性

项目成果

The Autism Impact Measure (AIM): Examination of Sensitivity to Change.

• DOI: 10.1002/aur.2397
• 发表时间: 2020-11
• 期刊: Autism research : official journal of the International Society for Autism Research
• 作者: Mazurek MO;Carlson C;Baker-Ericzén M;Butter E;Norris M;Barr C;Kanne S
• 通讯作者: Kanne S

Construct Validity of the Autism Impact Measure (AIM).

• DOI: 10.1007/s10803-018-3462-8
• 发表时间: 2020-07
• 期刊: Journal of autism and developmental disorders
• 影响因子: 3.9
• 作者: Mazurek MO;Carlson C;Baker-Ericzén M;Butter E;Norris M;Kanne S
• 通讯作者: Kanne S