N-acetyltryptamine Biology
N-acetyltryptamine Biology
批准号:
9150189
负责人:
David Klein
金额:
$0.49万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AgonistBindingBiologicalBiological AssayBiologyBloodBlood BanksBlood CirculationDevelopmentDiseaseExhibitsGeneticGoalsHumanImmune SeraMeasuresMelatoninMelatonin ReceptorsMethodsMonitorPhysiologyPlasmaPlayProductionPublished CommentRecoveryResearchRoleSignal TransductionSystemTimeUnited States National Institutes of HealthVariantbaseinterestprogramsvolunteer
中文摘要
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英文摘要
Signficant progress has been made in the development of an LC-MS/MS assay that detects day time levels of N-acetyltryptamine and melatonin in human plasma. The assay used deuterated internal standards to monitor recovery and to provide a basis for quantitatin. Theprinciples of this assay provide the basis for a high-throughput automated method.
Initial studies have established that N-acetyltryptamine is present in blood and that it exhibits significant variation amoung volunteers who have provided blood through the NIH Blood Bank Research Donor Program. Limited results precludes further comment.
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Pineal Regulation: Neural, transsynaptic and intracellular control
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Pineal Regulation: Molecular basis of development
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Pineal Regulation: Neural, transsynaptic and intracellular control mechanisms
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Pineal Regulation: Molecular basis of development
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Pineal Regulation: Developmental and Circadian Changes in the Transcriptome
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批准号:8553949
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财政年份:--
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Pineal Regulation: Control of arylalkylamine N-acetyltransferase
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依托单位:
Pineal Regulation: Control of arylalkylamine N-acetyltransferase
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资助金额:$43.22万
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依托单位:
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依托单位:
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