Ghana Cancer Registry - from Hospital to Population: a Pilot Study

加纳癌症登记处 - 从医院到人群：试点研究

• 批准号: 9243528
• 负责人: Ann Hsing
• 金额: $ 11.09万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-15 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9243528
• 关键词: Ghana; Cancer; Registry; Hospital; Population

DESCRIPTION (provided by applicant): Although communicable diseases still represent the major disease burden in Africa, preliminary data based on just ~1% of the continent's population, suggests that cancer incidence is increasing rapidly - faster than in the developed world - and that rates for specific types of cancers vary widely across Africa. In order to identif specific areas of focus for cancer control and prevention efforts, there is a dire need for high-quality cancer surveillance data, the kind that come from regional and national population-based cancer registries. To address this need in the West African country of Ghana, we propose here, as a first step, a hospital-based cancer registry based at the Korle-Bu Teaching Hospital, the largest hospital in Accra, the capital and largest city in Ghana, to develop effective procedures and training for hospital-wide case-finding/reporting covering the period 2009-2015 (Aim 1). We will develop procedures to link the cancer registry with existing tumor archives to create a registry-linked tumor bank and expedite assessment of pathology review and retrieval of pathology materials for molecular studies (Aim 2). Finally, we will survey other hospitals in Accra to assess the feasibility of future expansion to a population based cancer registry for all of Accr (Aim 3). Successful completion of our Aims will pave the way for a future population-based registry in Accra that will generate high-quality surveillance data to aid the effort of cancer control and prevention in Ghana. The Ghana registry data can also be used to compare with cancer patterns on African Americans to identify why persons of African descent are disproportionally affected by specific types of cancers, such as that of the prostate, renal cell carcinoma, and multiple myeloma.

描述（由申请人提供）：尽管传染病仍然是非洲的主要疾病负担，但基于非洲大陆人口约1%的初步数据表明，癌症发病率正在迅速增加-比发达国家更快-并且特定类型癌症的发病率在非洲各地差异很大。为了确定癌症控制和预防工作的具体重点领域，迫切需要高质量的癌症监测数据，这种数据来自区域和国家人口癌症登记处。为了满足西非国家加纳的这一需求，我们在此建议，作为第一步，在加纳首都和最大城市阿克拉最大的医院Korle-Bu教学医院建立一个基于医院的癌症登记处，为2009-2015年期间的全医院病例发现/报告制定有效的程序和培训（目标1）。我们将制定程序，将癌症登记处与现有肿瘤档案联系起来，以创建登记处联系的肿瘤库，并加快病理学审查评估和病理学材料检索，用于分子研究（目标2）。最后，我们将调查阿克拉的其他医院 评估未来扩展到所有Accr人群癌症登记的可行性（目标3）。我们的目标的成功完成将为今后在阿克拉进行基于人口的登记铺平道路，该登记将产生高质量的监测数据，以帮助加纳的癌症控制和预防工作。加纳的登记数据也可用于与非裔美国人的癌症模式进行比较，以确定为什么非洲裔人会受到特定类型癌症的影响，如前列腺癌，肾细胞癌和多发性骨髓瘤。