Bio-Specimen Assessment of Fire Effects (B-SAFE) Pregnancy Study
火灾影响生物样本评估 (B-SAFE) 妊娠研究
基本信息
- 批准号:9918374
- 负责人:
- 金额:$ 11.78万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-04-18 至 2023-03-31
- 项目状态:已结题
- 来源:
- 关键词:AffectAirAreaAutomobile DrivingBehaviorBiological MarkersBirthBurn injuryCaliforniaChemicalsChildCountyDataDevelopmentDisastersDistressEligibility DeterminationEmotionalExposure toFire - disastersFormaldehydeFutureGestational AgeGluesGoalsGrowth and Development functionHairHalogensHealthHealth PlanningHigh temperature of physical objectHumanHydrocortisoneInvestigationLocationLow Birth Weight InfantMasksMaternal and Child HealthMental DepressionMetalsMonitorMothersNatureOutcomeParticipantParticulate MatterPersonsPregnancyPregnancy OutcomePregnant WomenPropertyPsychosocial StressPublic HealthRainRecording of previous eventsReportingSan FranciscoSmokeSolventsStressStructureSurfaceSurveysSymptomsSystemTimeVisitVulnerable PopulationsWildfireWomanair filtrationarmbasebiobankcohortcritical periodfine particlesfollow-upindexingmetropolitanpost-traumatic symptomspostnatalpregnantpsychosocialresidencerespiratoryresponsesample collectionurban areavolatile organic compound
项目摘要
Abstract
On November 8th, 2018, the Camp Fire erupted in Northern California's Butte County. It was the deadliest
and most devastating wildfire in California history, with over 153,336 acres burned, 86 confirmed fatalities, over
18,500 structures destroyed including nearly 14,000 residences. Over 50,000 people were evacuated. This fire
was unusual not only in its scale and the rapidity of its spread to urban areas, but also in the vast area
blanketed in smoke that followed for a defined window of two weeks until the first rainfall. The wildfire smoke
plume spread quickly across vast areas of Northern California, and the air quality index was at hazardous
levels for most of Northern California for two weeks, with particulate matter <2.5 µm (PM2.5) concentrations
reaching the highest levels ever recorded in the region, including large metropolitan areas like Sacramento,
Oakland, San Francisco, and San Jose, affecting millions, including ~100,000 pregnant women. There are
widespread concerns about potential health impacts of these urban wildfires and how to mitigate their effects,
especially in vulnerable populations like pregnant women and their developing children. Exposure to extremely
unhealthy levels of wildfire PM2.5 for nearly two weeks for the majority who were unable to leave Northern
California are compounded by the unique composition of urban wildfire smoke. An array of potentially toxic
volatile organic compounds may be released with high temperature combustion of chemicals widely used in
building construction and interior furnishings, such as solvents, glues, metals, formaldehydes, and halogens.
Additionally, like other disasters that act as inherently unpredictable forces of nature that threaten person and
property, wildfires can induce emotional and psychosocial distress and potentially long-term consequences like
persistent post-traumatic stress symptoms and depression. Exposures to contaminants and stress in
combination could have serious long-term developmental consequences if delivered during critical periods in
pregnancy. The goal of this R21 is to rapidly establish a cohort of women who were at different stages of
pregnancy during the Camp Fire and their children, collect biosamples and survey information that will be used
in future studies to determine exposure loads, mechanistic responses, health biomarkers and developmental
outcomes. The cohort will have two eligibility arms: a) those residing within our target area closest to the fire
and within a feasible driving distance for in-person pregnancy, delivery, and postnatal visits and future follow-
up and b) women in Northern California pregnant during the Camp Fire who will complete an online survey and
mail in biospecimens. Participant near-surface wildfire PM2.5 exposure estimated from satellite and ground
monitor data, potential exposure-reducing behaviors, and residence aspects will be examined in relation to
maternal symptoms, stress biomarkers, and child gestational age and birthweight. The cohort and
biorepository established through this proposal will support future studies to understand and minimize the
developmental effects of future wildfires, as they increase in number, duration, and intensity.
摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Rebecca Jean Schmidt其他文献
Rebecca Jean Schmidt的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Rebecca Jean Schmidt', 18)}}的其他基金
Prenatal Environment And Child Health (PEACH) in ECHO
ECHO 中的产前环境和儿童健康 (PEACH)
- 批准号:
10746727 - 财政年份:2023
- 资助金额:
$ 11.78万 - 项目类别:
Folic Acid Prevention Pathways for ASD in High Risk Families
高危家庭中自闭症谱系障碍 (ASD) 的叶酸预防途径
- 批准号:
9116188 - 财政年份:2015
- 资助金额:
$ 11.78万 - 项目类别:
Folic Acid Prevention Pathways for ASD in High Risk Families
高危家庭中自闭症谱系障碍 (ASD) 的叶酸预防途径
- 批准号:
8917743 - 财政年份:2015
- 资助金额:
$ 11.78万 - 项目类别:
Exploring Interactions between Folate and Environmental Risk Factors for Autism
探索叶酸与自闭症环境风险因素之间的相互作用
- 批准号:
8260107 - 财政年份:2012
- 资助金额:
$ 11.78万 - 项目类别:
Exploring Interactions between Folate and Environmental Risk Factors for Autism
探索叶酸与自闭症环境风险因素之间的相互作用
- 批准号:
8474757 - 财政年份:2012
- 资助金额:
$ 11.78万 - 项目类别:
Exploring Interactions between Folate and Environmental Risk Factors for Autism
探索叶酸与自闭症环境风险因素之间的相互作用
- 批准号:
8628125 - 财政年份:2012
- 资助金额:
$ 11.78万 - 项目类别:
相似国自然基金
湍流和化学交互作用对H2-Air-H2O微混燃烧中NO生成的影响研究
- 批准号:51976048
- 批准年份:2019
- 资助金额:61.0 万元
- 项目类别:面上项目
相似海外基金
Development of acceptor materials for the large-area air-stable Organic Solar Cell with low energy loss
低能量损失大面积空气稳定有机太阳能电池受体材料的开发
- 批准号:
23K04913 - 财政年份:2023
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Air pollution and the health effects in South Asia: Comparison between urban and rural area and assessment of prevention with mask
南亚空气污染与健康影响:城乡比较及口罩预防评估
- 批准号:
18K10059 - 财政年份:2018
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Evaluation of the mercury pollution and elution risk of mercury in air, water and soil from bauxite mining area
铝土矿矿区空气、水和土壤中汞污染及汞洗脱风险评价
- 批准号:
18K18207 - 财政年份:2018
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Natural Fluid Transport Systems Limited: A novel “Microcomb” heat exchange module comprising a matrix of microtube air passageways designed to dramatically increase primary heat rejection surface area efficiency, and as a consequence provide significant i
Natural Fluid Transport Systems Limited:一种新颖的“微梳”热交换模块,包含微管空气通道矩阵,旨在显着提高主要散热表面积效率,从而提供显着的热交换效率。
- 批准号:
710501 - 财政年份:2014
- 资助金额:
$ 11.78万 - 项目类别:
GRD Proof of Concept
Prediction of minimum air temperature in the next morning in the sloping area and internet delivery of the prediction result
坡地次日清晨最低气温预测及预测结果网络发布
- 批准号:
26450343 - 财政年份:2014
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of interfacial area transport model of two-phase flow for improvement of ship drag reduction technology based on air lubrication method
基于空气润滑法改进船舶减阻技术的两相流界面区域输运模型的建立
- 批准号:
26289331 - 财政年份:2014
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Development and application of fast and large-area MEMS optical calorimeter at picowatt resolution in air at room temperature
室温空气中皮瓦分辨率快速大面积MEMS光学量热仪的研制与应用
- 批准号:
26420407 - 财政年份:2014
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Study on Optimal Air Traffic Control in Terminal Area using Topology Concept
基于拓扑概念的航站区空中交通优化控制研究
- 批准号:
25630388 - 财政年份:2013
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Study on Emission Control Area for Reducing Air Pollution From Shipping
减少船舶大气污染的排放控制区研究
- 批准号:
24710052 - 财政年份:2012
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Development of a method to estimate the traffic characteristic values for air pollution substance estimation in the Metropolitan area in East Asia
东亚都市区空气污染物质估算交通特征值估算方法的开发
- 批准号:
24510216 - 财政年份:2012
- 资助金额:
$ 11.78万 - 项目类别:
Grant-in-Aid for Scientific Research (C)