Training Program in Molecular, Cell, and Developmental Biology

分子、细胞和发育生物学培训项目

• 批准号: 8667085
• 负责人: Susan Strome
• 金额: $ 28.57万
• 依托单位: UNIVERSITY OF CALIFORNIA SANTA CRUZ
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8667085
• 关键词: Cellular biology; Developmental Biology; Molecular Biology; Training Programs

DESCRIPTION (provided by applicant): The goals of the UCSC Graduate Training Program in Molecular, Cell and Developmental Biology are to recruit highly motivated graduate students, provide them with critical thinking skills, expertise in experimental design and interpretation, an a strong framework of knowledge, while also amplifying their passion for inquiry and discovery. We strongly encourage interdisciplinary and collaborative research that crosses departmental, divisional, and even institutional boundaries. Intellectual, cultural, and socioeconomic diversity are prevalent in our graduate student population, and we constantly seek new approaches to attract and inspire students from under-represented groups. Our Training Program prepares students to pursue diverse careers in biomedical research, teaching, government, and industry. First-year trainees participate in three 6-week research rotations and in a core curriculum designed to train them in the logic of experimental analysis. Students learn how to evaluate published research, effectively argue scientific points, formulate hypotheses, design rigorous experiments, and write research manuscripts and proposals with intellectual depth. Students join a laboratory to pursue their Ph.D. thesis research in Spring of their first year. Second-year students train in the responsible conduct of research and take an oral qualifying exam. Third-year students present a full research seminar to the Training Program. Students at all stages participate in departmental seminars, research meetings, and journal clubs, and take advanced elective courses of their choosing. These broaden their training experience and promote interactions among trainees and faculty. Training culminates with a written Ph.D. dissertation and oral defense. Our Training Program includes 30 faculty from 5 departments, including the Departments of Molecular, Cell and Developmental Biology, Biomolecular Engineering, Chemistry and Biochemistry, Microbiology and Environmental Toxicology, and Physics. Participating laboratories are intermingled in 3 adjacent buildings on "science hill", which encourages interaction and collaboration. Research in the Training Program utilizes a wide variety of approaches, and is organized with interdisciplinary clusters of common interests (e.g. Cell Biology, Chromatin, Neurobiology, and RNA), thereby creating critical masses of researchers that foster mutual support and scientific creativity. Many training faculty work on systems that are directly relevant to human health, including stem cell biology, malaria, cholera, cancer biology, host-pathogen interactions, neurodegenerative diseases, and the responses of neurons to stroke and other damage. Other faculty carry out basic research that provides the foundation for understanding topics relevant to human health, including cell division, signaling, meiosis, chromatin organization, cell differentiation, and neurobiology. Our Training Grant, currently in its 14th year, supports 6 trainees. In this renewal, we are requesting support for 8 trainees. Training Grant positions will continue to be awarded to our most promising students.

描述（由申请人提供）：UCSC分子，细胞和发育生物学研究生培训计划的目标是招募高度积极的研究生，为他们提供批判性思维技能，实验设计和解释方面的专业知识，强大的知识框架，同时也增强他们对探索和发现的热情。我们强烈鼓励跨学科和合作研究，跨越部门，部门甚至机构的界限。在我们的研究生群体中，智力、文化和社会经济的多样性是普遍存在的，我们不断寻求新的方法来吸引和激励来自代表性不足的群体的学生。我们的培训计划为学生在生物医学研究、教学、政府和工业领域从事不同的职业做好准备。第一年的受训者参加三个为期6周的研究轮岗，并参加旨在训练他们实验分析逻辑的核心课程。学生学习如何评估已发表的研究，有效地论证科学观点，制定假设，设计严格的实验，并撰写具有智力深度的研究手稿和建议。学生们在第一年的春季加入实验室进行博士论文研究。二年级学生接受负责任的研究行为培训，并参加口头资格考试。三年级学生向培训计划提交一个完整的研究研讨会。各个阶段的学生都参加部门研讨会、研究会议和期刊俱乐部，并选修自己选择的高级选修课程。这些活动拓宽了他们的培训经验，促进了学员和教师之间的互动。培训的高潮是书面博士论文和口头答辩。学院现有分子、细胞与发育生物学、生物分子工程、化学与生物化学、微生物与环境毒理学、物理等5个系30名教师。参与的实验室在“科学山”的三座相邻建筑中相互交织，鼓励互动和合作。培训计划的研究采用多种方法，并以共同兴趣的跨学科集群（例如细胞生物学，染色质，神经生物学和RNA）组织，从而创造了培养相互支持和科学创造力的关键研究人员。许多培训教员研究与人类健康直接相关的系统，包括干细胞生物学、疟疾、霍乱、癌症生物学、宿主-病原体相互作用、神经退行性疾病以及神经元对中风和其他损伤的反应。其他教师进行基础研究，为理解与人类健康相关的主题提供基础，包括细胞分裂，信号传导，减数分裂，染色质组织，细胞分化和神经生物学。我们的培训补助金，目前是第14个年头，支持6名学员。在这次更新中，我们要求支持8名学员。培训补助金职位将继续授予最有前途的学生。