Cognitive Training for ADHD Treatment using a Gaming Model

描述（由申请人提供）：在这个第一阶段的项目中，Koronis生物医学技术公司（KBT）提议开发一种基于脑电图（EEG）的神经反馈视频游戏，使个体能够改善与注意缺陷多动障碍（ADHD）相关的神经认知过程。神经反馈是生物反馈的一种形式，在这种反馈中，脑电波活动的实时测量以一种方式呈现给个体，使他们能够有意识地控制脑电波活动的各个方面，以积极选择理想状态或减少不理想状态的时间。这个项目的一个主要目标是通过科学的依据来证明，在什么样的训练条件下，用户在广义认知训练中表现更好。这是一个重要而及时的研究目标，因为许多引人注目的失败都未能发现一般认知能力的收益，“移情”，作为训练的功能。第一阶段的研究项目将设计和构建一个脑电图神经反馈系统，将这种反馈整合到一个针对多动症儿童的演示视频游戏中，并进行一项试点人体研究，以评估和测试该系统的可用性。执行功能可训练性的积极证据将构成第二阶段适当控制的完整人体研究的基础。

DESCRIPTION (provided by applicant): In this phase I project, Koronis Biomedical Technologies (KBT) proposes to develop an electroencephalography (EEG) based neurofeedback video game to enable individuals to improve neurocognitive processes associated with Attention Deficit Hyperactivity Disorder (ADHD). Neurofeedback is a form of biofeedback in which real-time measures of brainwave activity are presented to the individual in a manner that enables them to willfully control aspects of their brainwave activity with the goal o actively selecting desirable states or reducing time in undesirable states. A major goal of this project is to demonstrate, through scientific basis, under what training conditions do users get better at generalized cognitive training. This is an important and timely research objective given a number of high profile failures to find gains in general cognitive abilities, "transference," as function of training. The phase I research program will design and construct an EEG Neurofeedback system that incorporates this feedback into a demonstration video game for children with ADHD and to conduct a pilot human study to evaluate and to test usability of the system. Positive evidence of trainability of executive function will form the basis of a properly controlled full human study in Phase II.