Training Program in Perinatal Biology and Medicine

描述(由申请者提供)：该培训计划为新生儿学和母胎医学医生(符合资格或获得其主要专业认证的医生)和已完成博士学位的基础科学家提供基础和临床-翻译研究培训。研究培训包括围产期/发育生理学、生物化学以及细胞和分子生物学的概念和技术。培训为期2-3年，为在儿科和妇产科或在与临床科室有直接联系的基础科学系内从事生殖医学的学术生涯做准备。受训者将在他们头两年的研究员/博士后培训期间表现出研究承诺和成就后被任命，这将与作为研究员/讲师的第四年和/或第五年的培训相平衡，但有助理教授的工资。在T32项目的第一年，学员与教师顾问一起选择基础研究项目和导师。研究导师、项目和实验室是从现有的T32教员中挑选出来的，但包括UCD医学院的教员广度和研究机会和设施。每个领域都包括临床翻译研究、整体动物研究、器官研究、细胞研究和分子研究，以便学员可以参与任何一个或几个级别的生物学研究。受训者参加回顾宫内发育和胎儿、产妇和新生儿生理学的研讨会。研究生院的课程涉及细胞培养、遗传学、发育生物学、细胞和分子生物学、同位素应用、生物统计学、数据处理和信息学、统计学、图形和成像、生物伦理学以及研究的伦理行为。提供了研究设计、摘要和手稿准备方面的研讨会计划。第二年和第三年致力于完成第一年开始的研究项目，并扩展到新的研究领域和新的研究技术。每个受训人员制定机构动物和临床研究方案，以解决人类和动物研究中涉及的技术和伦理问题。学员尽可能独立地计划和实施他们的研究项目，但要在教员的全面指导下进行。该计划提供基础和临床-翻译生物学调查的多学科培训，将最先进的研究技术与围产期医学和生物学的重要问题相结合。这种方法使受训者有能力独立并成功地进入基础科学或临床翻译科学的学术生涯。多年来，该培训项目的毕业生在国内和国际上都获得了很高的学术职位，并对开发和支持研究培训项目产生了重大影响。这种终极研究/学术领导是这个项目的主要目标。

DESCRIPTION (provided by applicant): This training program provides basic and clinical-translational research training for Neonatology and Maternal- Fetal Medicine physicians (board eligible or certified in their primary specialty) and Basic Scientists who have completed a PhD degree. The research training includes concepts and techniques in perinatal/developmental physiology, biochemistry, and cell and molecular biology. Training is for 2-3 years in preparation for academic careers in reproductive medicine within departments of Pediatrics and Obstetrics &-Gynecology or in basic science departments with direct links to the clinical departments. Trainees will be appointed after demonstrating research commitment and accomplishment during their 1st 2 years of fellowship/postdoctoral training, which will be balanced by 4th and/or 5th years of training as Fellow/Instructors but with Assistant Professor salaries. During the first year in the T32 program, trainees work with faculty advisors to select basic research projects and mentors. Research mentors, projects, and labs are selected among current T32 faculty, but include the breadth of faculty and research opportunities and facilities on the UCD Medical Campus. Each area includes clinical- translational, whole animal, organ, cell, and molecular research so that a trainee can participate at any one or several levels of biological investigation. Trainees attend seminars that review intrauterine development and fetal, maternal, and neonatal physiology. Courses in the graduate school dealing with cell culture, genetics, developmental biology, cell and molecular biology, isotope applications, biostatistics, data processing and informatics, statistics, graphics and imaging, bioethics, and ethical conduct of research are included. Seminar programs in research design and abstract and manuscript preparation are provided. The 2nd and 3rd years are devoted to the completion of the research projects begun in the 1st year and expansion into new areas of research and new research techniques. Each trainee develops institutional animal and clinical research protocols to address technical and ethical issues involved in human and animal research. Trainees plan and conduct their research projects as independently as they can, but with full faculty mentoring. This program provides multidisciplinary training in basic and clinical-translational biological investigation, integrating state-of-the-art research techniques with important questions in perinatal medicine and biology. This approach equips the trainees with the capacity to move independently and successfully into academic careers in either basic or clinical-translational science. Over many years, graduates of this training program have achieved high academic positions nationally and internationally and have had major impact on developing and supporting research training programs. Such ultimate research/academic leadership is a major aim of this program.