Identification of novel agonist of the Relaxin family peptide receptor 2 (RXFP2) as potential new therapeutics for testicular maldescent
Identification of novel agonist of the Relaxin family peptide receptor 2 (RXFP2) as potential new therapeutics for testicular maldescent
批准号:
9205645
负责人:
Marc Ferrer
金额:
$1.9万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
点击翻译按钮获取中文摘要
英文摘要
During this period, the NCGC has fostered and maintained over 180 active collaborations with both NIH and extramural investigators, facilitating drug discovery efforts across the entire spectrum of human disease. These efforts have led to over 100 high-throughput screens and nearly 60 medicinal chemistry campaigns, providing our collaborators and the general research community a wealth of publications and promising small molecule leads. In addition, the NCGC has undertaken a number of informatic challenges to make better use of existing drug and disease target information and provide the general public with easily accessible resources, further catalyzing the development of new therapies for human disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
3D Bioprinted Omentum tissue to model ovarian cancer metastasis
-
批准号:10683668
-
项目类别:
-
资助金额:$90.89万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
3D Bioprinted retina models for drug screening
-
批准号:10916043
-
项目类别:
-
资助金额:$226.91万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
3D Bioprinted lung cancer models for drug screening
-
批准号:10907367
-
项目类别:
-
资助金额:$226.91万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Targeting Tumor-derived exRNA-Containing microvesicles by high throughput screening
-
批准号:9359917
-
项目类别:
-
资助金额:$15.8万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
3D Bioprinting of human native-like tissues as disease-in-a-dish models for drug discovery
-
批准号:9355001
-
项目类别:
-
资助金额:$301.07万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Identification of Small Molecule Effectors that target the Fungal-Specific Kinase Drk1 as Novel Antifungal Drug Leads
-
批准号:9205652
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
PAC1 receptor antagonists as potential treatments for depression and atherosclerosis associated with chronic stress
-
批准号:9360500
-
项目类别:
-
资助金额:$3.75万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Identification of Small Molecule Inhibitors of PHF5A for Glioblastoma
-
批准号:9360504
-
项目类别:
-
资助金额:$3.75万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Small molecule inhibitor screen of MHC II processing pathways using influenza virus A/PR/8/34
-
批准号:9205649
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
High-throughput screens for compounds that reverse cellular toxicity of neurodegenerative disease-associated proteins in yeast models (alpha-synuclein)
-
批准号:9205648
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
A drug-screening platform for autism spectrum disorders using human neurons and astrocytes
-
批准号:9205632
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
HTS screening for inhibitors of HPV 16 E6/caspase 8 binding
-
批准号:9205653
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Identification of GPR52 antagonists as potential treatments for Huntington Disease
-
批准号:9205646
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Identification of small molecule inhibitors of miR-155 expression in Th17 cells
-
批准号:9205636
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Adaptation of an Organotypic 3 Dimensional Culture for High-Throughput Screening
-
批准号:9205647
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
3D Bioprinted skin models for drug screening
-
批准号:10683670
-
项目类别:
-
资助金额:$90.89万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
COVID-19: 3D Bioprinted Tissue Models for Respiratory Viruses
-
批准号:10907368
-
项目类别:
-
资助金额:$10.18万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Identification of small molecule inhibitors of Neutral Sphingomyelinase 2 (nSMase2) as a new therapeutic approach for the treatment of neurodegenerative disorders
-
批准号:9360493
-
项目类别:
-
资助金额:$3.75万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
A Novel Cell-Based Assay to Identify Small Molecules for Galactocerebrosidase (GALC)
-
批准号:9360503
-
项目类别:
-
资助金额:$3.75万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
Identification of small molecules that decrease the activity of the huntingtin gene promoter for the potential treatment of Huntington Disease
-
批准号:9205664
-
项目类别:
-
资助金额:$1.9万
-
财政年份:--
-
负责人:Marc Ferrer
-
依托单位:
国内基金
海外基金
登录
查看更多内容
Novel-miR-1134调控LHCGR的表达介导拟
穴青蟹卵巢发育的机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2025
-
负责人:崔文晓
-
依托单位:
novel-miR75靶向OPR2,CA2和STK基因调控人参真菌胁迫响应的分子机制研究
-
批准号:82304677
-
项目类别:青年科学基金项目
-
资助金额:30.00万元
-
批准年份:2023
-
负责人:边兴博
-
依托单位:
海南广藿香Novel17-GSO1响应p-HBA调控连作障碍的分子机制
-
批准号:82304658
-
项目类别:青年科学基金项目
-
资助金额:30万元
-
批准年份:2023
-
负责人:刘亚
-
依托单位:
白术多糖通过novel-mir2双靶向TRADD/MLKL缓解免疫抑制雏鹅的胸腺程序性坏死
-
批准号:32102747
-
项目类别:青年科学基金项目(C类)
-
资助金额:30.0万元
-
批准年份:2021
-
负责人:李婉雁
-
依托单位:
novel_circ_001042/miR-298-5p/Capn1轴调节线粒体能量代谢在先天性肛门直肠畸形发生中的作用机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:55万元
-
批准年份:2021
-
负责人:唐晓冰
-
依托单位:
novel-miR-59靶向HMGAs介导儿童早衰症细胞衰老的作用及机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:58万元
-
批准年份:2021
-
负责人:张瑜
-
依托单位:
novel_circ_008138/rno-miR-374-3p/SFRP4调控Wnt信号通路参与先天性肛门直肠畸形发生的分子机制研究
-
批准号:82070530
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2020
-
负责人:白玉作
-
依托单位:
miRNA-novel-272通过靶向半乳糖凝集素3调控牙鲆肠道上皮细胞炎症反应的机制研究
-
批准号:32002421
-
项目类别:青年科学基金项目
-
资助金额:24.0万元
-
批准年份:2020
-
负责人:修云吉
-
依托单位:
m6A修饰介导的lncRNA WEE2-AS1转录后novel-pri-miRNA剪切机制在胶质瘤恶性进展中的作用研究
-
批准号:82072775
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2020
-
负责人:薛皓
-
依托单位:
miRNA/novel_167靶向抑制Dmrt1的表达在红鳍东方鲀性别分化过程中的功能研究
-
批准号:31902347
-
项目类别:青年科学基金项目
-
资助金额:25.0万元
-
批准年份:2019
-
负责人:闫红伟
-
依托单位: