Mentoring in Cardiovascular Biology

我们第三阶段生物医学研究卓越中心(COBRE)计划的目标是继续 提供必要的强大基础设施、核心实验室支持和大学科学环境 指导优秀的调查人员，促进多学科和跨部门的合作 新奥尔良路易斯安那州立大学健康科学中心心血管生物学研究 (LSUHSC-否)。我们第一阶段和第二阶段Cobre计划的首要任务之一是增加 从科布雷过渡的初级研究人员获得NIH-R01心血管生物学研究资助的数量 支持R01资助的状态，并帮助这些人走上成功的研究职业道路。这 这一努力是朝着发展心血管中心的广泛机构倡议迈出的重要一步 在LSUHSC的卓越表现。在过去10年的资助中，我们建立了三个科学核心设施，这些设施具有 在推动科布雷和LSUHSC的其他研究人员的科学计划方面发挥了重要作用。我们 已经录取了16名优秀的小学生。调查人员通过我们的程序。在这些人中，有14人获得了校外 来自美国国立卫生研究院和/或美国心脏协会的奖励来自他们的Cobre项目。因此， 需要第三阶段的支持，以维持我们强大的基础设施和指导环境 在过去10年中随着我们的计划完成从Cobre到机构的过渡而发展起来 支持。以下是第111阶段计划的具体目标：1)提供支持以维持和 加强Cobre核心设施的基础设施和使用，这些设施对我们的功能至关重要 中心在LSUHSC的心血管研究任务，2)进一步增加 LSUHSC的研究人员通过支持在心血管疾病领域开展研究计划 Cobre试点项目和我们中心的指导使命，3)扩大专题、多学科 和心血管生物学的跨部门研究计划，促进合作 基础与临床-科学家的关系，4)。完成从Cobre支持的过渡 该计划是一个国家认可的跨学科卓越中心，由州和联邦政府资助。

The objective of our Phase III Center of Biomedical Research Excellence (COBRE) program is to continue to provide the strong infrastructure, core laboratory support, and collegial scientific environment necessary to mentor outstanding investigators and foster collaborations within the multidisciplinary and interdepartmental effort in cardiovascular biology at the Louisiana State University Health Sciences Center-New Orleans (LSUHSC-NO). One of the top priorities of our Phase I and Phase II COBRE program has been to increase the number of NIH-R01 grants in cardiovascular biology by transitioning Junior Investigators from COBRE support to R01-funded status and to launch these individuals on a successful research career path. This effort has been one major step to a broad institutional initiative to develop a Cardiovascular Center of Excellence at LSUHSC. Over the last 10 years of funding, we built three scientific core facilities that have been instrumental in advancing the scientific programs of COBRE and fellow researchers at LSUHSC. We have matriculated 16 outstanding Jr. Investigators through our program. Of these, 14 received extramural grant awards from NIH and/or the American Heart Association stemming from their COBRE projects. Thus, Phase III support is required to sustain the strong infrastructure and mentoring environment we have developed over the past 10 years as we finalize the transition of our program from COBRE to Institutional support. The following are the Specific Aims of the Phase 111 program: 1) To provide support to sustain and enhance the infrastructure and use of COBRE Core Facilities, which have been pivotal to the function of our Center's cardiovascular research mission at LSUHSC, 2) To further increase the critical mass of investigators at LSUHSC with research programs in the area of cardiovascular disease through the support of COBRE Pilot Projects and the mentoring mission of our Center, 3) To expand the thematic, multidisciplinary and interdepartmental research program in cardiovascular biology which fosters collaborative relationships between basic and clinician-scientists, 4). To finalize the transition from a COBRE supported program to a nationally recognized, interdisciplinary Center of Excellence with state and federal funding.