Mentoring in Cardiovascular Biology

心血管生物学辅导

• 批准号: 9321258
• 负责人: DANIEL R KAPUSTA
• 金额: $ 109.6万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-09 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9321258
• 关键词: American Heart Association; Animal Disease Models; Area; Award; Biology; Blood Vessels; Cardiovascular Diseases; Cardiovascular system; Career Choice; Cause of Death; Cell physiology; Centers of Research Excellence; Collaborations; Core Facility; Disease Progression; Environment; Extramural Activities; Fostering; Funding; Grant; Health Sciences; Human; In Vitro; Individual; Laboratories; Lead; Louisiana; Mentors; Mission; Molecular; Molecular Analysis; Phase; Pilot Projects; Process; Research; Research Infrastructure; Research Personnel; Research Training; Scientific Advances and Accomplishments; Scientist; Translational Research; United States; United States National Institutes of Health; Universities; Woman; men; multidisciplinary; programs; public health relevance; stem

DESCRIPTION (provided by applicant): The objective of our Phase IIl Center of Biomedical Research Excellence (COBRE) program is to continue to provide the strong infrastructure, core laboratory support, and collegial scientific environment necessary to mentor outstanding investigators and foster collaborations within the multidisciplinary and interdepartmental effort i cardiovascular biology at the Louisiana State University Health Sciences Center-New Orleans (LSUHSC-NO). One of the top priorities of our Phase I and Phase II COBRE program has been to increase the number of NIH-RO1 grants in cardiovascular biology by transitioning Junior Investigators from COBRE support to RO1-funded status and to launch these individuals on a successful research career path. This effort has been one major step to a broad institutional initiative to develop a Cardiovascular Center of Excellence at LSUHSC. Over the last 10 years of funding, we built three scientific core facilities that have been instrumental in advancing the scientific programs of COBRE and fellow researchers at LSUHSC. We have matriculated 16 outstanding Jr. Investigators through our program. Of these, 14 received extramural grant awards from NIH and/or the American Heart Association stemming from their COBRE projects. Thus, Phase III support is required to sustain the strong infrastructure and mentoring environment we have developed over the past 10 years as we finalize the transition of our program from COBRE to Institutional support. The following are the Specific Aims of the Phase III program: 1) To provide support to sustain and enhance the infrastructure and use of COBRE Core Facilities, which have been pivotal to the function of our Center's cardiovascular research mission at LSUHSC, 2) To further increase the critical mass of investigators at LSUHSC with research programs in the area of cardiovascular disease through the support of COBRE Pilot Projects and the mentoring mission of our Center, 3) To expand the thematic, multidisciplinary and interdepartmental research program in cardiovascular biology which fosters collaborative relationships between basic and clinician-scientists, 4). To finalize the transition from a COBRE supported program to a nationally recognized, interdisciplinary Center of Excellence with state and federal funding.

描述（由申请人提供）：我们的 IIl 期生物医学研究卓越中心 (COBRE) 计划的目标是继续提供强大的基础设施、核心实验室支持和学院科学环境，以指导杰出的研究人员并促进路易斯安那州立大学新奥尔良健康科学中心心血管生物学的多学科和跨部门工作中的合作 （LSUHSC-NO）。我们第一阶段和第二阶段 COBRE 计划的首要任务之一是通过将初级研究者从 COBRE 支持转变为 RO1 资助状态来增加心血管生物学领域 NIH-RO1 资助的数量，并让这些人走上成功的研究职业道路。这项努力是 LSUHSC 建立心血管卓越中心的广泛机构举措的重要一步。在过去 10 年的资助中，我们建立了三个科学核心设施，这些设施对于推进 COBRE 和 LSUHSC 研究人员的科学项目发挥了重要作用。通过我们的项目，我们已经录取了 16 名杰出的初级研究员。其中，14 人因其 COBRE 项目而获得了 NIH 和/或美国心脏协会的校外资助。因此，在我们完成项目从 COBRE 到机构支持的过渡时，需要第三阶段的支持来维持我们在过去 10 年中开发的强大基础设施和指导环境。以下是第三阶段计划的具体目标： 1) 提供支持，维持和加强 COBRE 核心设施的基础设施和使用，这对于我们中心在 LSUHSC 的心血管研究任务的功能至关重要，2) 通过 COBRE 试点项目的支持和我们中心的指导任务，进一步增加 LSUHSC 心血管疾病领域研究项目的研究人员数量， 3) 扩大心血管生物学的专题、多学科和跨部门研究计划，以促进基础科学家和临床医生-科学家之间的合作关系，4)。在州和联邦资助下，完成从 COBRE 支持的计划向全国认可的跨学科卓越中心的过渡。