Center for Research in Diagnostics and Discovery

诊断与发现研究中心

• 批准号: 9010912
• 负责人: W. Ian Lipkin
• 金额: $ 722.82万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-03-07 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9010912
• 关键词: Biological Assay; Biomedical Engineering; Communities; Country; Detection; Diagnostic; Disease susceptibility; Effectiveness; Epidemic; Genetic; Geographic Locations; Infectious Agent; Instruction; Integration Host Factors; Knowledge; Medical; Methodology; Molecular Biology; Pharmaceutical Preparations; Public Health; Research; Research Personnel; System; Systems Biology; Technology; Testing; Vaccines; accurate diagnosis; cost; diagnostic assay; improved; member; novel; pathogen; rapid diagnosis; tool

Accurate diagnosis is essential for proper medical treatment. Often this is confounded by the lack of or limitation of informative diagnostic assays and tools. Infectious agents rarely found in a given community or country commonly are not screened for as multiple single diagnostic assays are cost-prohibitive and tests for the most likely agent is deemed warranted. Yet it is increasingly clear that as infectious agents appear in , new geographic regions and contexts, the medical and public heath communities must improve and modernize the methodologies they utilize. The Center for Research in Diagnostics and Discovery aims to develop, validate and implement multiplex platforms and predictive strategies that will advance detection of novel pathogens, identify host factors that influence susceptibility of disease and predict effectiveness of drugs and vaccines. We will bring together researchers in the fields of molecular biology, systems biology, genetics, and bioengineering. We will also bring together members of the public health communities and conservation biologists. Together, the investigators in the Center for Research in Diagnostics and Discovery will advance knowledge and platforms for the detection of agents that are either previously unidentified, known causes of epidemics, or select agents by developing and utilizing systems that could be rapidly redirected for pathogens of any type.

准确的诊断对适当的医疗至关重要。通常这是由于缺乏或混淆