Optimizing Nanopore Protein Interactions

 描述(申请人提供)：电子生物科学(EBS)将开始研究最终实现基于纳米孔的多肽和氨基酸差异化的特征和相互作用。尽管一个完整的基于纳米孔的蛋白质表征系统有许多最终需要开发的组件，但在这两年的计划过程中，EBS将只专注于检测和区分方法，以证明基本的可行性和概念验证。这些研究产生的信息将为发展基于纳米孔的蛋白质表征概念提供基础，并最终将导致尖端蛋白质组学仪器的发展。

 DESCRIPTION (provided by applicant): Electronic BioSciences (EBS) will begin examining the characteristics and interactions that will eventually enable nanopore based differentiation of peptides and amino acids. Although there are numerous components of a complete nanopore based protein characterization system that will ultimately need to be developed, during the course of this two year program EBS will focus solely on the detection and differentiation methodologies in order to demonstrate basic feasibility and proof-of-concept. The information generated from these studies will provide the foundation for developing the nanopore based protein characterization concept and eventually will lead to the development of cutting edge proteomics instrumentation.