UTMB Clinical and Translational Science Award

UTMB 临床和转化科学奖

• 批准号: 9128790
• 负责人: Allan R. Brasier
• 金额: $ 373.89万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-18 至 2020-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9128790
• 关键词: Academy; Address; Adopted; Advocacy; African American; Aging; Appointment; Award; Budgets; Burn injury; Childhood; Clinical Research; Clinical Sciences; Clinical Trials; Communities; Community Healthcare; Course Content; Development; Devices; Diverse Workforce; Education; Educational Curriculum; Entrepreneurship; Environment; Ethics; Evaluation; Faculty; Fostering; Funding; Geriatrics; Goals; Growth; Health; Health Personnel; Health system; Hispanics; Historically Black Colleges and Universities; Home environment; Hospitals; Human; Hybrids; Impact evaluation; Individual; Industry; Institutes; Institution; Investments; Laboratories; Leadership; Medical; Mission; Modeling; Molecular; Monitor; Multi-Institutional Clinical Trial; Outcomes Research; Patient-Focused Outcomes; Patients; Pediatrics; Phase; Population; Positioning Attribute; Pregnancy; Publishing; Puerto Rico; Research; Research Activity; Research Infrastructure; Research Institute; Research Personnel; Research Support; Resource Sharing; Role; Science; Scientist; Site; Special Populations Research; Staging; System; Testing; Texas; Therapeutic; Training; Training Support; Translational Research; Translations; United States National Institutes of Health; Universities; Wages; Work; base; bench to bedside; career; cohort; commercialization; comparative effectiveness; data sharing; evidence base; experience; improved; innovation; inter-institutional; leadership development; learning community; medical schools; multidisciplinary; named group; novel; novel strategies; patient advocacy group; programs; quality assurance; science education; skills; tool; working group

The CTSA at the University of Texas Medical Branch (UTMB) is located within the Institute for Translational Science (ITS), one of three free-standing UTMB institutes, established in 2007. In its role as the home for clinical and translational research, the ITS provides primary tenure-earning faculty appointments to 7 early- career translational scientists. Over the past 5½ years, we have transformed UTMB's research culture, growing from an institution that solely valued individual laboratory-oriented research to one that embraces multidisciplinary translational team (MTT) approaches to addressing significant health problems. We have developed novel educational curricula, significant clinical research programs in special populations with multi- site clinical trials (CTs), and provided leadership in the Texas Regional CTSA consortium (TRCC) and nationally. The mission of the UTMB CTSA hub is to support the health goals of the nation by generating, testing and disseminating integrative team science, education and best practices through stakeholder involvement at all stages. Managed by a continuous improvement model using an Innovation Scorecard, the UTMB CTSA will address four specific aims, to: 1) Train a diverse workforce in the authentic skills needed to advance all phases of translational research. We have used the team environment as an educational framework to support the training of diverse learning communities. Our innovation, entrepreneurship, and team leadership curricula will be used to instill focused, career stage-appropriate competencies in our trainees. We have led in sharing and disseminating innovative educational content in entrepreneurship and team science throughout the consortium. 2). Engage stakeholders across all phases of translational research and CTs. We will extend our substantial bidirectional interactions with stakeholders from the community, patient advocacy groups, healthcare providers and our Health System to assess health needs, set CTSA priorities and disseminate competencies. 3). Integrate quality systems through all types of translational research, including CTs in special populations. We have provided leadership to a university-wide plan for sustainable support for high-quality CTs through the Office of Clinical Research, supported by an experienced director, an interoperable Clinical Trial Management System and staff to provide streamlined support for all phases of CT start-up, quality assurance monitoring, study management and GCP training. 4). Advance the conduct of translational research through MTT-based innovation. The UTMB CTSA hub is unique in the national consortium in its systematic application of a hybrid industry-academic MTT model, and have developed an evidence base on the formation, evaluation, impact and trajectories of successful MTTs. We will stimulate MTT innovation by promoting team development, leadership development by a unique Leadership Development Academy, and advancement of therapeutics and devices into Phase I/II CTs in our “Innovations in Molecular Therapeutics and Devices” Optional Module.

德克萨斯大学医学分部（UTMB）的CTSA位于转化研究所