FASEB SRC on Trace Elements in Biology and Medicine

FASEB SRC 关于生物学和医学中的微量元素

• 批准号: 9121906
• 负责人: DANIEL J. KOSMAN
• 金额: $ 1.76万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9121906
• 关键词: Area; Basic Science; Biochemistry; Biological; Biology; Cells; Cellular biology; Chemistry; Child Care; Clinical; Clinical Medicine; Collaborations; Communication; Copper; Development; Developmental Biology; Diabetes Mellitus; Discipline; Disease; Elements; Elevator; Ensure; Equilibrium; Eukaryota; Family member; Feedback; Fertilization; Fostering; Functional disorder; Gender; Genetic; Goals; Health; Heart Hypertrophy; Homeostasis; Human; Image; Immune response; Immunity; In Situ; Individual; Iron; Knowledge; Leadership; Life; Malignant Neoplasms; Manganese; Medicine; Mentors; Metabolic; Metabolic Diseases; Metabolism; Metals; Micronutrients; Molecular; Monitor; Motor; National origin; Nerve Degeneration; Neuraxis; Neuropathy; Organism; Outcome; Oxygen; Participant; Patients; Persons; Physically Handicapped; Physiological; Physiological Processes; Plants; Play; Positioning Attribute; Postdoctoral Fellow; Process; Reaction; Recommendation; Recording of previous events; Regulation; Research; Research Personnel; Resolution; Role; Schedule; Science; Scientist; Selenium; Series; Services; Students; Surveys; Technical Expertise; Techniques; Trace Elements; Trace metal; Training; Transition Elements; Underrepresented Minority; Vascular Plant; Woman; Work; Zinc; base; biomedical scientist; career; career development; diabetic; disability; experience; health care delivery; human disease; interest; meetings; microorganism; next generation; novel therapeutic intervention; nutrition; pathogen; peer; posters; programs; protein aggregation; protein structure; public health relevance; research and development; respiratory; skills; success; symposium; trafficking; uptake

 DESCRIPTION (provided by applicant): The 2016 FASEB Conference on Trace Elements in Biology and Medicine will take place at the Big Sky Conference Center, outside of Bozeman, MT, June 5-10, 2016. This is one of the original SRCs, meeting biennially since 1983, the first of the now larger group of conferences that focus on the broad subject of metals in biology. What distinguishes this SRC from these others (e.g. GRC "Metals in Biology" and "Cell Biology of Metals") is its focus on how essential micronutrients such as iron (Fe), copper (Cu), zinc (Zn), manganese (Mn) and selenium (Se) contribute to the physiologic interaction between humans and the biosphere, e.g. humans as hosts for bacterial and fungal pathogens; metals and metabolic disorders such as diabetics and respiratory dysfunction; metals and protein aggregation-associated neurodegeneration. This breadth of impact is reflected in the breadth of the scientific program described and the PIs and their trainees who will be brought together. The program will span a range of scientific interests from developmental biology, genetics, and biochemistry, to chemistry, nutrition, and clinical medicine. Session topics will cover trace element uptake, trafficking, and regulation in microorganisms, plants, and higher eukaryotes including humans; the role of trace elements in immunity and metabolic disorders; metals in neurodegeneration. Cutting-edge techniques useful in monitoring trace elements in cells will be discussed. A notable strength of this conference series has been its ability to unite research scientists focused on the molecular details of trace element metabolism with scientist-clinicians studying the direct impact of trace elements on human health, nutrition, and disease; this Conference has been "translational" before the word became topical. Last, a primary aim of this SRC has always been to provide a forum in which trainees and new investigators can hone their skills and credentials, positioning them to take over leadership of the "Trace Elements" field in the coming decades. We will be bringing together established investigators and trainees to promote communication, mentoring, and collaborations. The ultimate goal of this conference series is to foster the ongoing development of new therapeutic interventions with respect to human diseases and disorders that, at least in part, reflect a pathophysiology related to trace element metabolism.